scholarly journals The use of small intestinal submucosa graft for hypospadias repair: Pilot study

2013 ◽  
Vol 11 (4) ◽  
pp. 415-420 ◽  
Author(s):  
Hazem Orabi ◽  
Ahmed S. Safwat ◽  
Ahmed Shahat ◽  
Hisham M. Hammouda
Keyword(s):  
Pilot Study ◽  
Small Intestinal Submucosa ◽  
Hypospadias Repair ◽  
Small Intestinal ◽  
Intestinal Submucosa

Use of Single Layer Small Intestinal Submucosa for Long Segment Ureteral Replacement: A Pilot Study.

2004 ◽  
Vol 171 (5) ◽  
pp. 1939-1942 ◽  
Author(s):  
AHMED EL-ASSMY ◽  
ASHRAF T. HAFEZ ◽  
MOHAMED T. EL-SHERBINY ◽  
MOHAMED ABD EL-HAMID ◽  
TAREK MOHSEN ◽  
...  
Keyword(s):  
Pilot Study ◽  
Single Layer ◽  
Small Intestinal Submucosa ◽  
Ureteral Replacement ◽  
Small Intestinal ◽  
Intestinal Submucosa

Percutaneous Vein Occlusion with Small Intestinal Submucosa: An Experimental Pilot Study in Swine and Sheep

2007 ◽  
Vol 30 (4) ◽  
pp. 725-730 ◽  
Author(s):  
Man Deuk Kim ◽  
Hanno Hoppe ◽  
Dusan Pavcnik ◽  
John A. Kaufman ◽  
Barry T. Uchida ◽  
...  
Keyword(s):  
Pilot Study ◽  
Small Intestinal Submucosa ◽  
Vein Occlusion ◽  
Small Intestinal ◽  
Intestinal Submucosa

Comparison of Small Intestinal Submucosa–covered and Noncovered Nitinol Stents in Sheep Iliac Arteries: A Pilot Study

2002 ◽  
Vol 13 (5) ◽  
pp. 489-498 ◽  
Author(s):  
Naoyuki Toyota ◽  
Dusan Pavcnik ◽  
William VanAlstine ◽  
Barry T. Uchida ◽  
Hans A. Timmermans ◽  
...  
Keyword(s):  
Pilot Study ◽  
Small Intestinal Submucosa ◽  
Iliac Arteries ◽  
Nitinol Stents ◽  
Small Intestinal ◽  
Intestinal Submucosa

A pilot study to evaluate the effectiveness of small intestinal submucosa used to repair spinal ligaments in the goat

2002 ◽  
Vol 2 (3) ◽  
pp. 188-196 ◽  
Author(s):  
Eric H. Ledet ◽  
Allen L. Carl ◽  
Darryl J. DiRisio ◽  
Michael P. Tymeson ◽  
Lucille B. Andersen ◽  
...  
Keyword(s):  
Pilot Study ◽  
Small Intestinal Submucosa ◽  
Spinal Ligaments ◽  
Small Intestinal ◽  
Intestinal Submucosa

Small Intestinal Submucosa as an Intra-Articular Ligamentous Graft Material: A Pilot Study in Dogs

1994 ◽  
Vol 07 (03) ◽  
pp. 124-128 ◽  
Author(s):  
S. F. Badylak ◽  
J. P. Toombs ◽  
K. D. Shelbourne ◽  
M. C. Hiles ◽  
G. C. Lantz ◽  
...  
Keyword(s):  
Pilot Study ◽  
Connective Tissue ◽  
Cruciate Ligament ◽  
Small Intestinal Submucosa ◽  
Graft Material ◽  
Cranial Cruciate Ligament ◽  
Immune Mediated ◽  
Ligamentous Structure ◽  
Small Intestinal ◽  
Intestinal Submucosa

SummaryThis pilot study was performed to determine the potential for using small intestinal submucosa (SIS) xenografts for intra-articular ligament reconstruction. Porcine SIS was used to replace the excised cranial cruciate ligament (CCL) in five normal dogs. Grafts were evaluated histologically at 10, 12, 16, and 26 weeks after implantation. Two grafts were evaluated biomechanically at 26 weeks. All of the SIS neoligaments appeared macroscopically as white fibrous bands. The histological appearance progressed, with time, from disorganized immature connective tissue to large bundles of organized connective tissue, covered by a synovial membrane, that resembled the native CCL. There was no histological evidence of immune-mediated nor any foreign body reaction to the xenogeneic SIS graft material. The neoligaments 26 weeks after implantation had a maximum force to failure that was 16.2 and 21.4 times greater than the original SIS graft material and were 7.6 and 11.1 percent as strong as the contralateral control CCLs. We conclude that porcine SIS, used as an intra-articular graft material to replace the normal CCL in dogs, supported host tissue ingrowth, remodelled to form a ligamentous structure, and is worthy of further investigation.Small intestinal submucosa was used to replace the excised cranial cruciate ligament (CCL) in five normal dogs. The histo-logical appearance of the grafts progressively changed, with time, from disorganized immature connective tissue to large bundles of organized connective tissue that resembled the native CCL. Graft strength increased between implantation and 26 weeks after the operation, however remained weaker than controls.

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