Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.01.073 ◽

2006 ◽

Vol 16 (8) ◽

pp. 2105-2108 ◽

Author(s):

Tao Jiang ◽

Kelli L. Kuhen ◽

Karen Wolff ◽

Hong Yin ◽

Kimberly Bieza ◽

...

Keyword(s):

Reverse Transcriptase ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

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Design, synthesis, and biological evaluation of novel 5-Alkyl-6-Adamantylmethylpyrimidin-4(3H)-ones as HIV-1 non-nucleoside reverse-transcriptase inhibitors

Chemical Biology & Drug Design ◽

10.1111/cbdd.12765 ◽

2016 ◽

Vol 88 (3) ◽

pp. 380-385 ◽

Author(s):

Wenxin Li ◽

Boshi Huang ◽

Dongwei Kang ◽

Erik De Clercq ◽

Dirk Daelemans ◽

...

Keyword(s):

Reverse Transcriptase ◽

Biological Evaluation ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

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Design, Synthesis and Biological Evaluations of Novel Oxindoles as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. Part 1.

10.1002/chin.200629096 ◽

2006 ◽

Vol 37 (29) ◽

Author(s):

Tao Jiang ◽

Kelli L. Kuhen ◽

Karen Wolff ◽

Hong Yin ◽

Kimberly Bieza ◽

...

Keyword(s):

Reverse Transcriptase ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

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Design, Synthesis, and Biological Evaluation of 1-[(2-Benzyloxyl/alkoxyl)methyl]-5-halo-6-aryluracils as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with an Improved Drug Resistance Profile

Journal of Medicinal Chemistry ◽

10.1021/jm201506e ◽

2012 ◽

Vol 55 (5) ◽

pp. 2242-2250 ◽

Author(s):

Xiaowei Wang ◽

Jianfang Zhang ◽

Yang Huang ◽

Ruiping Wang ◽

Liang Zhang ◽

...

Keyword(s):

Drug Resistance ◽

Reverse Transcriptase ◽

Biological Evaluation ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

Resistance Profile ◽

Drug Resistance Profile ◽

Synthesis And Biological Evaluation ◽

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ChemInform Abstract: Structure-Based Design, Synthesis, and Biological Evaluation of Novel Pyrrolyl Aryl Sulfones (I): HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors Active at Nanomolar Concentrations.

10.1002/chin.200030099 ◽

2010 ◽

Vol 31 (30) ◽

pp. no-no

Author(s):

Marino Artico ◽

et al. et al.

Keyword(s):

Reverse Transcriptase ◽

Biological Evaluation ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

Abstract Structure ◽

Synthesis And Biological Evaluation ◽

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Design, synthesis, and biological evaluations of novel quinolones as HIV-1 non-nucleoside reverse transcriptase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.05.073 ◽

2006 ◽

Vol 16 (16) ◽

pp. 4246-4251 ◽

Author(s):

David Ellis ◽

Kelli L. Kuhen ◽

Beth Anaclerio ◽

Baogen Wu ◽

Karen Wolff ◽

...

Keyword(s):

Reverse Transcriptase ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

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Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of 2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)- ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, Also Active Against the Y181C Variant

Journal of Medicinal Chemistry ◽

10.1021/jm0309856 ◽

2004 ◽

Vol 47 (4) ◽

pp. 928-934 ◽

Author(s):

Rino Ragno ◽

Antonello Mai ◽

Gianluca Sbardella ◽

Marino Artico ◽

Silvio Massa ◽

...

Keyword(s):

Reverse Transcriptase ◽

Computer Aided Design ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

Computer Aided ◽

Aided Design ◽

Anti Hiv ◽

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Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.6b00738 ◽

2016 ◽

Vol 59 (17) ◽

pp. 7991-8007 ◽

Author(s):

Dongwei Kang ◽

Zengjun Fang ◽

Zhenyu Li ◽

Boshi Huang ◽

Heng Zhang ◽

...

Keyword(s):

Drug Resistance ◽

Reverse Transcriptase ◽

Reverse Transcriptase Inhibitors ◽

Pyrimidine Derivatives ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

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Structure-Based Design, Synthesis, and Biological Evaluation of Novel Pyrrolyl Aryl Sulfones: HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors Active at Nanomolar Concentrations

Journal of Medicinal Chemistry ◽

10.1021/jm9901125 ◽

2000 ◽

Vol 43 (9) ◽

pp. 1886-1891 ◽

Author(s):

Marino Artico ◽

Romano Silvestri ◽

Eugenia Pagnozzi ◽

Biancamaria Bruno ◽

Ettore Novellino ◽

...

Keyword(s):

Reverse Transcriptase ◽

Biological Evaluation ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

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Design, Synthesis, and Biological Evaluations of Novel Oxindoles as HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. Part 2.

10.1002/chin.200630120 ◽

2006 ◽

Vol 37 (30) ◽

Author(s):

Yun He ◽

et al. et al.

Keyword(s):

Reverse Transcriptase ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

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Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.01.066 ◽

2006 ◽

Vol 16 (8) ◽

pp. 2109-2112 ◽

Author(s):

Tao Jiang ◽

Kelli L. Kuhen ◽

Karen Wolff ◽

Hong Yin ◽

Kimberly Bieza ◽

...

Keyword(s):

Reverse Transcriptase ◽

Reverse Transcriptase Inhibitors ◽

Nucleoside Reverse Transcriptase Inhibitors ◽

Design Synthesis ◽

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