Monogenic lupus due to DNASE1L3 deficiency in a pediatric patient with urticarial rash, hypocomplementemia, pulmonary hemorrhage, and immune-complex glomerulonephritis

2021 ◽  
pp. 104262
Author(s):  
Rabia Miray Kisla Ekinci ◽  
Sibel Balci ◽  
Dilek Ozcan ◽  
Bahriye Atmis ◽  
Atil Bisgin
Keyword(s):  
Immune Complex ◽  
Pediatric Patient ◽  
Pulmonary Hemorrhage ◽  
Immune Complex Glomerulonephritis ◽  
Urticarial Rash

Effect of Thrombocytopenia on the Onset of Immune Complex Glomerulonephritis

Nephron ◽  
1992 ◽  
Vol 60 (1) ◽  
pp. 49-55 ◽  
Author(s):  
T. Ideura ◽  
M. Ogasawara ◽  
S. Tomura ◽  
T. Ida ◽  
Y. Chida ◽  
...  
Keyword(s):  
Immune Complex ◽  
Immune Complex Glomerulonephritis

Nephrotic Syndrome Associated with Varicella Infection

PEDIATRICS ◽  
1985 ◽  
Vol 75 (6) ◽  
pp. 1127-1131
Author(s):  
Ching-Yuang Lin ◽  
Hey-Chi Hsu ◽  
Han-Yang Hung
Keyword(s):  
Nephrotic Syndrome ◽  
Immune Complex ◽  
Alternative Pathway ◽  
Virus Antigen ◽  
Varicella Infection ◽  
Immune Complex Glomerulonephritis ◽  
Varicella Virus ◽  
Complex Deposition ◽  
Properdin Factor B ◽  
Antigen Antibody

A 4-year-old boy developed nephrotic syndrome following varicella infection. Serologic studies during the early phase of the disease demonstrated a decrease in serum C3, C4, and properdin factor B. Renal biopsy revealed an acute proliferative glomerulonephritis with deposition of immunoglobulins A (IgA) and M, C3, Clq, and varicella virus antigen in the glomerulus, suggesting an immune complex deposition. Ultrastructurally, this suggested a postinfectious immune complex glomerulonephritis. These phenomena suggested that varicella virus antigen antibody complexes were deposited in the glomerulus and activated the classic and alternative pathway of complements, leading to an immune complex glomerulonephritis. During the nephrotic phase, an increase in OKT8 cells and decrease of the OKT4 cells were demonstrated. Two months later, this alteration returned to normal as the renal disease was in remission. This change of lymphocyte subsets during varicella infection may play a role in the pathogenesis of nephrotic syndrome.

Macrophage depletion reduces disease pathology in factor H dependent immune complex glomerulonephritis

2018 ◽  
Vol 102 ◽  
pp. 130-131
Author(s):  
Alexander Jacob ◽  
Jessica Reynolds ◽  
Anthony Chang ◽  
Richard Quigg ◽  
Jessy Alexander
Keyword(s):  
Immune Complex ◽  
Factor H ◽  
Immune Complex Glomerulonephritis ◽  
Macrophage Depletion

IgM-immune complex glomerulonephritis associated with sarcoidosis

2006 ◽  
Vol 10 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Hiroshi Kanamori ◽  
Maiko Ota ◽  
Hiroya Takeoka ◽  
Kenji Osafune ◽  
Seibun Yonezu ◽  
...  
Keyword(s):  
Immune Complex ◽  
Immune Complex Glomerulonephritis

The Pathogenesis of Autologous Immune Complex Glomerulonephritis in Rats

1983 ◽  
pp. 337-348
Author(s):  
Christine K. Abrass ◽  
Wayne A. Border ◽  
Richard J. Glassock
Keyword(s):  
Immune Complex ◽  
Immune Complex Glomerulonephritis
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