Donor Derived Exosomes Expressing Lung Associated Self-antigens (Collagen V and K alpha 1 Tubulin) in Acute and Chronic Rejection Following Human Lung Transplantation

M. Gunasekaran; Z. Xu; D. Nayak; M. Sharma; R. Hachem; T. Mohanakumar

doi:10.1016/j.healun.2016.01.280

Donor Derived Exosomes Expressing Lung Associated Self-antigens (Collagen V and K alpha 1 Tubulin) in Acute and Chronic Rejection Following Human Lung Transplantation

The Journal of Heart and Lung Transplantation ◽

10.1016/j.healun.2016.01.280 ◽

2016 ◽

Vol 35 (4) ◽

pp. S102

Author(s):

M. Gunasekaran ◽

Z. Xu ◽

D. Nayak ◽

M. Sharma ◽

R. Hachem ◽

...

Keyword(s):

Lung Transplantation ◽

Chronic Rejection ◽

Human Lung ◽

Self Antigens

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302: Alloimmunity Induced Remodeling of Airway Epithelium Exposes Cryptic Self Antigens (Kα1 Tubulin & CollagenV), Leading to Autoimmunity and Chronic Rejection Following Human Lung Transplantation

The Journal of Heart and Lung Transplantation ◽

10.1016/j.healun.2008.11.309 ◽

2009 ◽

Vol 28 (2) ◽

pp. S171

Author(s):

D. Saini ◽

S. Ramachandran ◽

M. Liu ◽

G. Simon ◽

N. Steward ◽

...

Keyword(s):

Lung Transplantation ◽

Airway Epithelium ◽

Chronic Rejection ◽

Human Lung ◽

Self Antigens

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De novo development of dsa and autoantibodies to lung associated self-antigens is associated with upregulation of transcription factor Zbtb7a: Role in chronic rejection following human lung transplantation

Human Immunology ◽

10.1016/j.humimm.2015.07.063 ◽

2015 ◽

Vol 76 ◽

pp. 44

Author(s):

Deepak Nayak ◽

Fangyu Zhou ◽

Ramsey Hachem ◽

Daniel Kreisel ◽

Thalachallour Mohanakumar

Keyword(s):

Transcription Factor ◽

Lung Transplantation ◽

Chronic Rejection ◽

Human Lung ◽

De Novo ◽

Self Antigens

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Decline in Club Cell Secretory Proteins, Exosomes Induction and Immune Responses to Lung Self-antigens, Kα1 Tubulin and Collagen V, Leading to Chronic Rejection after Human Lung Transplantation

Transplantation Journal ◽

10.1097/tp.0000000000003428 ◽

2020 ◽

Vol Publish Ahead of Print ◽

Author(s):

Yoshihiro Itabashi ◽

Ranjithkumar Ravichandran ◽

Sandhya Bansal ◽

Ankit Bharat ◽

Ramsey Hachem ◽

...

Keyword(s):

Immune Responses ◽

Lung Transplantation ◽

Chronic Rejection ◽

Human Lung ◽

Secretory Proteins ◽

Club Cell ◽

Self Antigens

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392: Interaction between α-1-Antitrypsin (AAT) and A-Defensins in Regulating Immune Responses Leading to Chronic Rejection Following Human Lung Transplantation

The Journal of Heart and Lung Transplantation ◽

10.1016/j.healun.2009.11.406 ◽

2010 ◽

Vol 29 (2) ◽

pp. S130-S130

Author(s):

D. Saini ◽

S. Ramachandran ◽

N. Steward ◽

A. Aloush ◽

R. Hachem ◽

...

Keyword(s):

Immune Responses ◽

Lung Transplantation ◽

Chronic Rejection ◽

Human Lung

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Exosomes With Lung Self-antigens, Kα1Tubulin and Collagen V, as Biomarker for Bronchiolitis Obliterans Syndrome Following Human Lung Transplantation

The Journal of Heart and Lung Transplantation ◽

10.1016/j.healun.2018.01.064 ◽

2018 ◽

Vol 37 (4) ◽

pp. S34

Author(s):

T. Mohanakumar ◽

M. Gunasekaran ◽

M. Sharma ◽

S. Elnahas ◽

S. Biswas Roy ◽

...

Keyword(s):

Lung Transplantation ◽

Bronchiolitis Obliterans ◽

Human Lung ◽

Bronchiolitis Obliterans Syndrome ◽

Self Antigens

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Autoimmunity to collagen-V may lead to chronic rejection after human lung transplantation

The Journal of Heart and Lung Transplantation ◽

10.1016/j.healun.2004.11.078 ◽

2005 ◽

Vol 24 (2) ◽

pp. S59-S60

Author(s):

A. Bharat ◽

E. Trulock ◽

G.A. Patterson ◽

A. Aloush ◽

T. Mohanakumar

Keyword(s):

Lung Transplantation ◽

Chronic Rejection ◽

Human Lung

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The significance of bronchial associated lymphoid tissue in human lung transplantation: Is there an association with acute and chronic rejection?

The Journal of Heart and Lung Transplantation ◽

10.1016/s1053-2498(99)80028-x ◽

1999 ◽

Vol 18 (1) ◽

pp. 41

Keyword(s):

Lung Transplantation ◽

Chronic Rejection ◽

Lymphoid Tissue ◽

Human Lung

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233 Epitope Switch of Self-Antigen Collagen V Is Associated with Th-17 Phenotype and Autoimmune Responses: Role in Chronic Rejection Following Human Lung Transplantation

The Journal of Heart and Lung Transplantation ◽

10.1016/j.healun.2011.01.240 ◽

2011 ◽

Vol 30 (4) ◽

pp. S83-S84

Author(s):

V. Tiriveedhi ◽

N. Angaswamy ◽

D. Brand ◽

J. Weber ◽

R. Hacheem ◽

...

Keyword(s):

Lung Transplantation ◽

Chronic Rejection ◽

Human Lung ◽

Th 17 ◽

Self Antigen

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345 Ligation of Human Airway Epithelial Cells Antibodies Specific to K- α1-Tubulin Leads to Activation of HIF-1α Dependent Induction of Fibrinogenic Growth Factors: Role in the Pathogenesis of Chronic Rejection Following Human Lung Transplantation

The Journal of Heart and Lung Transplantation ◽

10.1016/j.healun.2011.01.352 ◽

2011 ◽

Vol 30 (4) ◽

pp. S119-S120

Author(s):

V. Tiriveedhi ◽

T. Mohanakumar

Keyword(s):

Growth Factors ◽

Epithelial Cells ◽

Lung Transplantation ◽

Chronic Rejection ◽

Human Lung ◽

Airway Epithelial Cells ◽

Airway Epithelial ◽

Human Airway ◽

Human Airway Epithelial Cells

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Lipid raft facilitated ligation of K-α1-tubulin by specific antibodies on epithelial cells: Role in pathogenesis of chronic rejection following human lung transplantation

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2010.07.063 ◽

2010 ◽

Vol 399 (2) ◽

pp. 251-255 ◽

Cited By ~ 17

Author(s):

Venkataswarup Tiriveedhi ◽

Nataraju Angaswamy ◽

Joseph Weber ◽

T. Mohanakumar

Keyword(s):

Epithelial Cells ◽

Lung Transplantation ◽

Lipid Raft ◽

Chronic Rejection ◽

Human Lung ◽

Specific Antibodies

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