Corrigendum to “Functional characterization of the polyketide synthase gene required for ochratoxin A biosynthesis in Penicillium verrucosum” [Int. J. Food Microbiol. 161 (2013) 172–181]

2013 ◽  
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Abdelhamid Abbas ◽  
Avril Coghlan ◽  
John O'Callaghan ◽  
Carlos García-Estrada ◽  
Juan-Francisco Martín ◽  
...  
2013 ◽  
Vol 161 (3) ◽  
pp. 172-181 ◽  
Author(s):  
John O'Callaghan ◽  
Avril Coghlan ◽  
Abdelhamid Abbas ◽  
Carlos García-Estrada ◽  
Juan-Francisco Martín ◽  
...  

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Toxins ◽  
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Jonathan Selvaraj ◽  
...  

Microbiology ◽  
2003 ◽  
Vol 149 (12) ◽  
pp. 3485-3491 ◽  
Author(s):  
J. O'Callaghan ◽  
M. X. Caddick ◽  
A. D. W. Dobson

Ochratoxin A is an important nephrotoxic and nephrocarcinogenic mycotoxin, produced by Aspergillus ochraceus as a polyketide-derived secondary metabolite. A portion of a putative polyketide synthase gene (pks) involved in the biosynthesis of this mycotoxin was cloned by using a suppression subtractive hybridization PCR-based approach. The predicted amino acid sequence of the 1·4 kb clone shared 28–35 % identity to acyl transferase regions from fungal polyketide synthases found in the databases. Based on reverse transcription PCR studies, the pks gene is expressed only under ochratoxin A permissive conditions and only during the early stages of the mycotoxin synthesis. A mutant in which the pks gene has been interrupted cannot synthesize ochratoxin A. This report is the first of the cloning and characterization of a gene involved in ochratoxin A biosynthesis.


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Scott E. Baker ◽  
...  

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Soon Gyu Hong ◽  
...  

2016 ◽  
Vol 35 (10) ◽  
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Girija Aiswarya ◽  
Vijayanathan Mallika ◽  
Luis A. J. Mur ◽  
Eppurathu Vasudevan Soniya

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