286 Phase 3 studies in atopic dermatitis with the novel, nonsteroidal topical phosphodiesterase 4 inhibitor, crisaborole

Journal of Investigative Dermatology ◽

10.1016/j.jid.2016.02.316 ◽

2016 ◽

Vol 136 (5) ◽

pp. S50 ◽

Author(s):

A.S. Paller ◽

W.L. Tom ◽

R.S. Call ◽

L. Eichenfield ◽

D. Forsha ◽

...

Keyword(s):

Atopic Dermatitis ◽

The Novel ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

A Novel Nonsteroidal, Topical Anti-inflammatory, Phosphodiesterase 4 Inhibitor, Crisaborole Ointment, Reduced Pruritus and Signs of Atopic Dermatitis in 2 Phase 3 Studies in Children and Adults

10.1542/peds.141.1_meetingabstract.251 ◽

2018 ◽

Author(s):

Adelaide A. Hebert ◽

Lawrence F. Eichenfield ◽

Mark G. Lebwohl ◽

Amy S. Paller ◽

Eric L. Simpson ◽

...

Keyword(s):

Atopic Dermatitis ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Anti Inflammatory ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

Phase 3 Studies Treating Children and Adult Patients with Mild to Moderate Atopic Dermatitis with Crisaborole Ointment, a Novel, Nonsteroidal, Topical Anti-inflammatory, Phosphodiesterase 4 Inhibitor

10.1542/peds.141.1_meetingabstract.275 ◽

2018 ◽

Author(s):

Amy S. Paller ◽

Wynnis L. Tom ◽

Mark G. Lebwohl ◽

Mark Boguniewicz ◽

Lawrence F. Eichenfield ◽

...

Keyword(s):

Atopic Dermatitis ◽

Adult Patients ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Anti Inflammatory ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

Crisaborole topical ointment, 2%: A novel, nonsteroidal, topical antiinflammatory, phosphodiesterase 4 inhibitor: Results from two phase 3 studies treating children and adult patients with mild to moderate atopic dermatitis

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2016.02.337 ◽

2016 ◽

Vol 74 (5) ◽

pp. AB86 ◽

Keyword(s):

Atopic Dermatitis ◽

Adult Patients ◽

Phase 3 ◽

Two Phase ◽

Phosphodiesterase 4 ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

Difamilast ointment, a selective phosphodiesterase 4 inhibitor, in paediatric patients with atopic dermatitis: A phase 3 randomised double‐blind, vehicle‐controlled trial

British Journal of Dermatology ◽

10.1111/bjd.20655 ◽

2021 ◽

Author(s):

H. Saeki ◽

N. Baba ◽

K. Ito ◽

D. Yokota ◽

H. Tsubouchi

Keyword(s):

Atopic Dermatitis ◽

Controlled Trial ◽

Phase 3 ◽

Double Blind ◽

Phosphodiesterase 4 ◽

Paediatric Patients ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

SAT0392 Work Productivity Improvement Associated with Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Results of A Phase 3, Randomized, Controlled Trial

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.4419 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 736.1-736 ◽

Author(s):

F. Zhang ◽

T. Tencer ◽

S. Li

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Work Productivity ◽

Phase 3 ◽

Productivity Improvement ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

SAT0568 Long-Term Work Productivity Improvement Associated with Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Pooled Analysis of 3 Phase 3 Studies

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2015-eular.3590 ◽

2015 ◽

Vol 74 (Suppl 2) ◽

pp. 866.2-866 ◽

Author(s):

F. Zhang ◽

Z. Clancy ◽

S. Li

Keyword(s):

Psoriatic Arthritis ◽

Work Productivity ◽

Pooled Analysis ◽

Phase 3 ◽

Productivity Improvement ◽

Phosphodiesterase 4 ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

The Effect Of The Novel Phosphodiesterase-4 Inhibitor MEM 1414 On The Allergen-induced Responses In mild Asthma

10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5613 ◽

2010 ◽

Author(s):

Brianr R. Leaker ◽

Dave Singh ◽

Peter J. Barnes ◽

margaret Imrie ◽

Richard Hughes ◽

...

Keyword(s):

Mild Asthma ◽

Induced Responses ◽

The Novel ◽

Phosphodiesterase 4 ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

LB0001 Long-Term (52-Week) Results of a Phase 3, Randomized, Controlled Trial of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-eular.526 ◽

2013 ◽

Vol 72 (Suppl 3) ◽

pp. A163-A163 ◽

Author(s):

A. Kavanaugh ◽

P. J. Mease ◽

A. O. Adebajo ◽

J. Wollenhaupt ◽

C. Hu ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

SAT0402 Apremilast, an Oral Phosphodiesterase 4 Inhibitor, in Patients with Psoriatic Arthritis: Pharmacodynamic Results of A Phase 3, Randomized, Controlled Trial (PALACE 1)

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.3878 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 739.4-740 ◽

Author(s):

P. Schafer ◽

P. Chen ◽

L. Fang ◽

A. Wang ◽

R. Chopra

Keyword(s):

Randomized Controlled Trial ◽

Psoriatic Arthritis ◽

Controlled Trial ◽

Phase 3 ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

078. LONG-TERM WORK PRODUCTIVITY IMPROVEMENT ASSOCIATED WITH APREMILAST, AN ORAL PHOSPHODIESTERASE 4 INHIBITOR, IN PATIENTS WITH PSORIATIC ARTHRITIS: POOLED ANALYSIS OF THREE PHASE 3 STUDIES

Rheumatology ◽

10.1093/rheumatology/kex062.078 ◽

2017 ◽

Vol 56 (suppl_2) ◽

Author(s):

Frank Zhang ◽

Zoe Clancy ◽

Stan Li ◽

Farhan Mughal

Keyword(s):

Psoriatic Arthritis ◽

Work Productivity ◽

Pooled Analysis ◽

Phase 3 ◽

Productivity Improvement ◽

Phosphodiesterase 4 ◽

Three Phase ◽

Phosphodiesterase 4 Inhibitor

Download Full-text