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A phase II randomized trial to evaluate the long-term (12-week) efficacy and safety of OC-01 (varenicline solution) nasal spray for dry eye disease: The MYSTIC study
The Ocular Surface
◽
10.1016/j.jtos.2021.12.007
◽
2021
◽
Author(s):
Hugo Quiroz-Mercado
◽
Everardo Hernandez-Quintela
◽
Kuei Hsun Chiu
◽
Eugenia Henry
◽
Jeffrey A. Nau
Keyword(s):
Randomized Trial
◽
Nasal Spray
◽
Phase Ii
◽
Dry Eye
◽
Dry Eye Disease
◽
Eye Disease
◽
Efficacy And Safety
Download Full-text
Related Documents
Cited By
References
Efficacy and Safety of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease: the ONSET-2 Phase 3, Randomized Trial
Ophthalmology
◽
10.1016/j.ophtha.2021.11.004
◽
2021
◽
Author(s):
David Wirta
◽
Patrick Vollmer
◽
James Paauw
◽
Kuei-Hsun Chiu
◽
Eugenia Henry
◽
...
Keyword(s):
Randomized Trial
◽
Nasal Spray
◽
Dry Eye
◽
Signs And Symptoms
◽
Dry Eye Disease
◽
Eye Disease
◽
Efficacy And Safety
◽
Phase 3
Download Full-text
Efficacy and safety of two new formulations of artificial tears in subjects with dry eye disease: a 3-month, multicenter, active-controlled, randomized trial
Clinical Ophthalmology
◽
10.2147/opth.s78184
◽
2015
◽
pp. 665
◽
Cited By ~ 25
Author(s):
Peter Simmons
◽
Haixia Liu
◽
Cindy Carlisle-Wilcox
◽
Joseph Vehige
Keyword(s):
Randomized Trial
◽
Dry Eye
◽
Dry Eye Disease
◽
Eye Disease
◽
Efficacy And Safety
◽
Artificial Tears
Download Full-text
Clinical Trial to Evaluate the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The ONSET Study)
Case Medical Research
◽
10.31525/ct1-nct03920215
◽
2019
◽
Author(s):
Keyword(s):
Clinical Trial
◽
Nasal Spray
◽
Dry Eye
◽
Signs And Symptoms
◽
Dry Eye Disease
◽
Eye Disease
◽
Long Term Follow Up
Download Full-text
ONSET-1 Phase 2b Randomized Trial to Evaluate the Safety and Efficacy of OC-01 (Varenicline Solution) Nasal Spray on Signs and Symptoms of Dry Eye Disease
Cornea
◽
10.1097/ico.0000000000002941
◽
2021
◽
Vol Publish Ahead of Print
◽
Author(s):
David Wirta
◽
Gail L. Torkildsen
◽
Blair Boehmer
◽
David A. Hollander
◽
Edward Bendert
◽
...
Keyword(s):
Randomized Trial
◽
Nasal Spray
◽
Dry Eye
◽
Signs And Symptoms
◽
Dry Eye Disease
◽
Eye Disease
◽
Safety And Efficacy
Download Full-text
Efficacy and Safety of 0.1% Cyclosporine a Cationic Emulsion in the Treatment of Severe Dry Eye Disease: A Multicenter Randomized Trial
European Journal of Ophthalmology
◽
10.5301/ejo.5000779
◽
2016
◽
Vol 26
(4)
◽
pp. 287-296
◽
Cited By ~ 61
Author(s):
Andrea Leonardi
◽
Gysbert Van Setten
◽
Mourad Amrane
◽
Dahlia Ismail
◽
Jean-Sebastien Garrigue
◽
...
Keyword(s):
Randomized Trial
◽
Dry Eye
◽
Cyclosporine A
◽
Dry Eye Disease
◽
Eye Disease
◽
Efficacy And Safety
◽
Multicenter Randomized Trial
Download Full-text
A Clinical Phase II Study to Assess Efficacy, Safety, and Tolerability of Waterfree Cyclosporine Formulation for Treatment of Dry Eye Disease
Ophthalmology
◽
10.1016/j.ophtha.2019.01.024
◽
2019
◽
Vol 126
(6)
◽
pp. 792-800
◽
Cited By ~ 7
Author(s):
David L. Wirta
◽
Gail L. Torkildsen
◽
Helen R. Moreira
◽
John D. Lonsdale
◽
Joseph B. Ciolino
◽
...
Keyword(s):
Phase Ii
◽
Dry Eye
◽
Phase Ii Study
◽
Dry Eye Disease
◽
Eye Disease
◽
Clinical Phase
Download Full-text
Long-term Natural History of Dry Eye Disease from the Patient's Perspective
Ophthalmology
◽
10.1016/j.ophtha.2015.10.011
◽
2016
◽
Vol 123
(2)
◽
pp. 425-433
◽
Cited By ~ 23
Author(s):
Jeffrey P. Lienert
◽
Laura Tarko
◽
Miki Uchino
◽
William G. Christen
◽
Debra A. Schaumberg
Keyword(s):
Natural History
◽
Dry Eye
◽
Dry Eye Disease
◽
Eye Disease
◽
Patient’S Perspective
◽
History Of
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A Randomized, Placebo-Controlled Phase II Clinical Trial of 0.01% or 0.02% Cyclosporin A with 3% Trehalose in Patients with Dry Eye Disease
Journal of Ocular Pharmacology and Therapeutics
◽
10.1089/jop.2020.0104
◽
2021
◽
Vol 37
(1)
◽
pp. 4-11
Author(s):
Jeongah Shin
◽
Chang Rae Rho
◽
Joon Young Hyon
◽
Tae-Young Chung
◽
Kyung Chul Yoon
◽
...
Keyword(s):
Clinical Trial
◽
Cyclosporin A
◽
Phase Ii
◽
Dry Eye
◽
Dry Eye Disease
◽
Phase Ii Clinical Trial
◽
Eye Disease
Download Full-text
Efficacy and safety of dual-polymer hydroxypropyl guar- and hyaluronic acid-containing lubricant eyedrops for the management of dry-eye disease: a randomized double-masked clinical study
Clinical Ophthalmology
◽
10.2147/opth.s177176
◽
2018
◽
Vol Volume 12
◽
pp. 2499-2508
◽
Cited By ~ 3
Author(s):
Marc Labetoulle
◽
Stefanie Schmickler
◽
David Galarreta
◽
Daniel Boehringer
◽
Abayomi Ogundele
◽
...
Keyword(s):
Hyaluronic Acid
◽
Clinical Study
◽
Dry Eye
◽
Dry Eye Disease
◽
Eye Disease
◽
Efficacy And Safety
◽
Hydroxypropyl Guar
Download Full-text
Efficacy and Safety of a Cationic Emulsion in the Treatment of Moderate to Severe Dry Eye Disease: A Randomized Controlled Study
European Journal of Ophthalmology
◽
10.5301/ejo.5000830
◽
2016
◽
Vol 26
(6)
◽
pp. 546-555
◽
Cited By ~ 9
Author(s):
Pierre-Yves Robert
◽
Béatrice Cochener
◽
Mourad Amrane
◽
Dahlia Ismail
◽
Jean-Sébastien Garrigue
◽
...
Keyword(s):
Dry Eye
◽
Dry Eye Disease
◽
Randomized Controlled Study
◽
Controlled Study
◽
Eye Disease
◽
Efficacy And Safety
◽
Randomized Controlled
Download Full-text
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