Peptide amphiphile nanofiber hydrogel delivery of sonic hedgehog protein to the cavernous nerve to promote regeneration and prevent erectile dysfunction

Peptide amphiphile nanofiber hydrogel delivery of sonic hedgehog protein to the penis and cavernous nerve, suppresses intrinsic and extrinsic apoptotic signaling mechanisms, which are an underlying cause of erectile dysfunction

Nanomedicine Nanotechnology Biology and Medicine ◽

10.1016/j.nano.2021.102444 ◽

2021 ◽

pp. 102444

Author(s):

Sarah Martin ◽

Daniel A. Harrington ◽

Samuel Ohlander ◽

Samuel I. Stupp ◽

Kevin T. McVary ◽

...

Keyword(s):

Erectile Dysfunction ◽

Sonic Hedgehog ◽

Peptide Amphiphile ◽

Apoptotic Signaling ◽

Cavernous Nerve ◽

Signaling Mechanisms

Faculty Opinions recommendation of Peptide amphiphile nanofiber hydrogel delivery of sonic hedgehog protein to the cavernous nerve to promote regeneration and prevent erectile dysfunction.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726747781.793523877 ◽

2016 ◽

Author(s):

Selim Cellek

Keyword(s):

Erectile Dysfunction ◽

Sonic Hedgehog ◽

Peptide Amphiphile ◽

Faculty Opinions recommendation of Peptide amphiphile nanofiber hydrogel delivery of sonic hedgehog protein to the cavernous nerve to promote regeneration and prevent erectile dysfunction.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726747781.793538161 ◽

2017 ◽

Author(s):

Suks Minhas

Keyword(s):

Erectile Dysfunction ◽

Sonic Hedgehog ◽

Peptide Amphiphile ◽

Regeneration of the cavernous nerve by Sonic hedgehog using aligned peptide amphiphile nanofibers

Biomaterials ◽

10.1016/j.biomaterials.2010.10.003 ◽

2011 ◽

Vol 32 (4) ◽

pp. 1091-1101 ◽

Cited By ~ 83

Author(s):

Nicholas L. Angeloni ◽

Christopher W. Bond ◽

Yi Tang ◽

Daniel A. Harrington ◽

Shuming Zhang ◽

...

Keyword(s):

Sonic Hedgehog ◽

Peptide Amphiphile ◽

055 Optimization of Sonic Hedgehog Delivery from Self-assembled Nanofiber Hydrogels to Prevent Erectile Dysfunction in a Cavernous Nerve Crush Model

Journal of Sexual Medicine ◽

10.1016/j.jsxm.2016.12.069 ◽

2017 ◽

Vol 14 (2) ◽

pp. e27-e28

Author(s):

S. Choe ◽

D.A. Harrington ◽

S.I. Stupp ◽

K. McVary ◽

C.A. Podlasek

Keyword(s):

Erectile Dysfunction ◽

Sonic Hedgehog ◽

Nerve Crush ◽

Cavernous Nerve ◽

Self Assembled

1427: Decreased Sonic Hedgehog Protein, Erectile Dysfunction and Cavernous Nerve Injury

10.1016/s0022-5347(18)38652-x ◽

2004 ◽

Vol 171 (4S) ◽

pp. 376-376

Author(s):

Carol A. Podlasek ◽

Yi Tang ◽

Cynthia L. Meroz ◽

Helen L. Korolis ◽

Kevin E. McKenna ◽

...

Keyword(s):

Erectile Dysfunction ◽

Nerve Injury ◽

Sonic Hedgehog ◽

Cavernous Nerve ◽

Cavernous Nerve Injury

755 PEPTIDE AMPHIPHILE NANOFIBER DELIVERY OF SONIC HEDGEHOG PROTEIN TO REDUCE SMOOTH MUSCLE APOPTOSIS IN THE PENIS AFTER CAVERNOUS NERVE RESECTION

10.1016/j.juro.2011.02.1780 ◽

2011 ◽

Vol 185 (4S) ◽

Author(s):

Christopher Bond ◽

Nicholas Angeloni ◽

Daniel Harrington ◽

Samuel Stupp ◽

Kevin McKenna ◽

...

Keyword(s):

Smooth Muscle ◽

Sonic Hedgehog ◽

Peptide Amphiphile ◽

Peptide Amphiphile Nanofiber Delivery of Sonic Hedgehog Protein to Reduce Smooth Muscle Apoptosis in the Penis after Cavernous Nerve Resection

Journal of Sexual Medicine ◽

10.1111/j.1743-6109.2010.02001.x ◽

2011 ◽

Vol 8 (1) ◽

pp. 78-89 ◽

Cited By ~ 37

Author(s):

Christopher W. Bond ◽

Nicholas L. Angeloni ◽

Daniel A. Harrington ◽

Samuel I. Stupp ◽

Kevin E. McKenna ◽

...

Keyword(s):

Smooth Muscle ◽

Sonic Hedgehog ◽

Peptide Amphiphile ◽

1400: A Randomized Phase II Trial Evaluating the Importance of Early Erectile Dysfunction Rehabilitation and Unilateral Autologous Sural Nerve Grafting in Patients Undergoing a Unilateral Cavernous Nerve Sparing Radical Prostatectomy for Clinically localized PR

10.1016/s0022-5347(18)31601-x ◽

2007 ◽

Vol 177 (4S) ◽

pp. 461-461 ◽

Cited By ~ 1

Author(s):

Christopher G. Wood ◽

David Chang ◽

Run Wang ◽

Yu Shen ◽

Curtis A. Pettaway ◽

...

Keyword(s):

Erectile Dysfunction ◽

Radical Prostatectomy ◽

Phase Ii ◽

Sural Nerve ◽

Phase Ii Trial ◽

Nerve Sparing ◽

Nerve Grafting ◽

Cavernous Nerve ◽

Randomized Phase Ii

672: Regulation of Cavernous Nerve Injury-Induced Apoptosis by Sonic Hedgehog

10.1016/s0022-5347(18)30912-1 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 225-225

Author(s):

Carol A. Podlasek ◽

Yi Tang ◽

Cynthia L. Meraz ◽

Kevin E. McKenna ◽

Kevin T. McVary

Keyword(s):

Nerve Injury ◽

Sonic Hedgehog ◽

Cavernous Nerve ◽

Induced Apoptosis ◽

Cavernous Nerve Injury