Corrigendum to “Fractalkine/CX3CL1 enhances GABA synaptic activity at serotonin neurons in the rat dorsal raphe nucleus”

Neuroscience ◽  
2010 ◽  
Vol 165 (4) ◽  
pp. 1559-1560
Author(s):  
L. Kirby ◽  
S. Heinisch
Keyword(s):  
Dorsal Raphe Nucleus ◽  
Dorsal Raphe ◽  
Raphe Nucleus ◽  
Synaptic Activity ◽  
Serotonin Neurons ◽  
Dorsal Raphé

Trafficking of neurokinin-1 receptors in serotonin neurons is controlled by substance P within the rat dorsal raphe nucleus

2009 ◽  
Vol 29 (12) ◽  
pp. 2303-2314 ◽  
Author(s):  
Baptiste Lacoste ◽  
Mustapha Riad ◽  
Marc-Olivier Ratté ◽  
Sandra M. Boye ◽  
Daniel Lévesque ◽  
...  
Keyword(s):  
Substance P ◽  
Dorsal Raphe Nucleus ◽  
Dorsal Raphe ◽  
Raphe Nucleus ◽  
Serotonin Neurons ◽  
Neurokinin 1 ◽  
Dorsal Raphé

scholarly journals Chronic methylphenidate treatment during adolescence has long-term effects on monoaminergic function

2018 ◽  
Vol 33 (1) ◽  
pp. 109-121 ◽  
Author(s):  
Mathieu Di Miceli ◽  
Adesina Omoloye ◽  
Benjamin Gronier
Keyword(s):  
Ventral Tegmental Area ◽  
Dorsal Raphe Nucleus ◽  
Late Adolescence ◽  
Dorsal Raphe ◽  
Raphe Nucleus ◽  
Late Adolescent ◽  
Serotonin Neurons ◽  
Ventral Tegmental ◽  
Dorsal Raphé

Background: Psychostimulants like methylphenidate or D-amphetamine are often prescribed for attention deficit and hyperactivity disorders in children. Whether such drugs can be administered into a developing brain without consequences in adulthood is still an open question. Methods: Here, using in vivo extracellular electrophysiology in anesthetised preparations, combined with behavioural assays, we have examined the long-term consequences in adulthood of a chronic methylphenidate oral administration (5 mg/kg/day, 15 days) in early adolescent (post-natal day 28) and late adolescent (post-natal day 42) rats, by evaluating body weight change, sucrose preference (indicator of anhedonia), locomotor sensitivity to D-amphetamine and electrical activities of ventral tegmental area dopamine and dorsal raphe nucleus serotonin neurons. Results: Chronic methylphenidate treatment during early or late adolescence did not induce weight deficiencies and anhedonia-like behaviours at adulthood. However, it increased bursting activities of dorsal raphe nucleus serotonin neurons. Furthermore, chronic methylphenidate treatment during early but not during late adolescence enhanced D-amphetamine-induced rearing activity, as well as ventral tegmental area dopamine cell excitability (firing, burst and population activity), associated with a partial desensitisation of dopamine D2 auto-receptors. Conclusions: We have demonstrated here that early, but not late, adolescent exposure to oral methylphenidate may induce long-lasting effects on monoamine neurotransmission. The possible clinical implication of these data will be discussed.

Targeting conditional gene modification into the serotonin neurons of the dorsal raphe nucleus by viral delivery of the Cre recombinase

2003 ◽  
Vol 24 (1) ◽  
pp. 139-147 ◽  
Author(s):  
Etienne Thévenot ◽  
Francine Côté ◽  
Philippe Colin ◽  
Yi He ◽  
Hélène Leblois ◽  
...  
Keyword(s):  
Dorsal Raphe Nucleus ◽  
Cre Recombinase ◽  
Dorsal Raphe ◽  
Raphe Nucleus ◽  
Gene Modification ◽  
Serotonin Neurons ◽  
Dorsal Raphé
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