Leukocyte Transfusion and the Development of the Continuous-Flow Blood Cell Separator

2011 ◽  
Vol 25 (4) ◽  
pp. 344-350 ◽  
Author(s):  
Emil J. Freireich
Keyword(s):  
Blood Cell ◽  
Continuous Flow ◽  
Cell Separator ◽  
Blood Cell Separator

Leukocyte and Platelet Collection from Normal Donors with the Continuous Flow Blood Cell Separator

Transfusion ◽  
1971 ◽  
Vol 11 (2) ◽  
pp. 94-101 ◽  
Author(s):  
R. G. Graw ◽  
G. P. Herzig ◽  
R. J. Eisel ◽  
S. Perry
Keyword(s):  
Blood Cell ◽  
Continuous Flow ◽  
Cell Separator ◽  
Blood Cell Separator

Collection of Lymphocytes on a Continuous-Flow Blood Cell Separator

Vox Sanguinis ◽  
1976 ◽  
Vol 31 (6) ◽  
pp. 446-450
Author(s):  
C.R. Pentycross ◽  
P.A.M. Walden ◽  
K.D. Bagshawe
Keyword(s):  
Blood Cell ◽  
Continuous Flow ◽  
Cell Separator ◽  
Blood Cell Separator

scholarly journals Development of a practical oral dexamethasone premedication schedule leading to improved granulocyte yields with the continuous-flow centrifugal blood cell separator

Blood ◽  
1978 ◽  
Vol 52 (1) ◽  
pp. 249-253 ◽  
Author(s):  
EF Winton ◽  
WR Vogler
Keyword(s):  
Blood Cell ◽  
Continuous Flow ◽  
Granulocyte Count ◽  
Cell Separator ◽  
Oral Dexamethasone ◽  
Blood Cell Separator

Abstract Studies were conducted to improve the yield of granulocytes collected for transfusion from normal donors by means of the continuous-flow centrifugal blood cell separator. Nonleukapheresed donors were medicated with varying schedules of corticosteroids to learn the magnitude and duration of granulocytosis. Normal donors were medicated with varying schedules of corticosteroids prior to a 4-hr leukapheresis and the granulocyte yields determined. It was found that maximum yields (32.2 x 10(9) granulocytes) were obtained by use of dexamethasone given orally 12 and 3 hr prior to leukapheresis. There was a good correlation between the yields and the circulating granulocyte count at the start and during the procedure.

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