A Peripherally Acting Nav1.7 Sodium Channel Blocker Reverses Hyperalgesia and Allodynia on Rat Models of Inflammatory and Neuropathic Pain

2012 ◽  
Vol 2012 ◽  
pp. 368-369
Author(s):  
S.E. Abram
Keyword(s):  
Neuropathic Pain ◽  
Sodium Channel ◽  
Channel Blocker ◽  
Sodium Channel Blocker ◽  
Rat Models

A Peripherally Acting Nav1.7 Sodium Channel Blocker Reverses Hyperalgesia and Allodynia on Rat Models of Inflammatory and Neuropathic Pain

2009 ◽  
Vol 109 (3) ◽  
pp. 951-958 ◽  
Author(s):  
Erin McGowan ◽  
Scott B. Hoyt ◽  
Xiaohua Li ◽  
Kathryn A. Lyons ◽  
Catherine Abbadie
Keyword(s):  
Neuropathic Pain ◽  
Sodium Channel ◽  
Channel Blocker ◽  
Sodium Channel Blocker ◽  
Rat Models

Butyl 2-(4-[1.1′-biphenyl]-4-yl-1H-imidazol-2-yl)ethylcarbamate, a potent sodium channel blocker for the treatment of neuropathic pain

2007 ◽  
Vol 17 (6) ◽  
pp. 1746-1749 ◽  
Author(s):  
Anne-Marie Liberatore ◽  
Jocelyne Schulz ◽  
Christine Favre-Guilmard ◽  
Jacques Pommier ◽  
Jacques Lannoy ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Sodium Channel ◽  
Channel Blocker ◽  
Sodium Channel Blocker

HYP-17, a novel voltage-gated sodium channel blocker, relieves inflammatory and neuropathic pain in rats

2017 ◽  
Vol 153 ◽  
pp. 116-129 ◽  
Author(s):  
Jee Youn Lee ◽  
Yoo Lim Kam ◽  
Jungae Oh ◽  
Dong Hyun Kim ◽  
Jin-Sung Choi ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Sodium Channel ◽  
Channel Blocker ◽  
Sodium Channel Blocker ◽  
Voltage Gated Sodium Channel ◽  
Voltage Gated

A novel benzazepinone sodium channel blocker with oral efficacy in a rat model of neuropathic pain

2013 ◽  
Vol 23 (12) ◽  
pp. 3640-3645 ◽  
Author(s):  
Scott B. Hoyt ◽  
Clare London ◽  
Catherine Abbadie ◽  
John P. Felix ◽  
Maria L. Garcia ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Sodium Channel ◽  
Rat Model ◽  
Channel Blocker ◽  
Sodium Channel Blocker

Potent analgesic effects of a putative sodium channel blocker M58373 on formalin-induced and neuropathic pain in rats

2006 ◽  
Vol 536 (3) ◽  
pp. 248-255 ◽  
Author(s):  
Yasushige Akada ◽  
Shinichi Ogawa ◽  
Ken-ichi Amano ◽  
Yuka Fukudome ◽  
Fumiaki Yamasaki ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Sodium Channel ◽  
Channel Blocker ◽  
Sodium Channel Blocker ◽  
Analgesic Effects
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