scholarly journals Actions of beta adrenergic blocking agents on arterial blood pressure and heart rate in the conscious dog.

1983 ◽  
Vol 33 ◽  
pp. 213
Author(s):  
Katsuhiko Yano ◽  
Katsuhide Nishi
1969 ◽  
Vol 47 (2) ◽  
pp. 213-216 ◽  
Author(s):  
W. A. Mahon ◽  
D. J. Campbell

Normal adult patients were infused with epinephrine in a dose of 0.15 μg/kg per minute given intravenously before and after beta adrenergic blockade with propranolol, 0.1 mg/kg and butoxamine 1 mg/kg. Epinephrine produced a significant rise of heart rate, cardiac output, and blood pressure and an elevation of free fatty acids and glucose. The beta adrenergic blocking agents reversed all these effects with the exception that a rise in systolic blood pressure occurred. These findings are consistent with the hypothesis that a rise in free fatty acid is mediated by beta adrenergic stimulation whereas the rise in blood glucose produced by epinephrine is probably due to alpha adrenergic stimulation. In man, the beta adrenergic effects of butoxamine include a reversal of most of the cardiovascular as well as the metabolic effects produced by epinephrine infusion.


1975 ◽  
Vol 18 (2) ◽  
pp. 148-152 ◽  
Author(s):  
Milton L. Hoefle ◽  
Stephen G. Hastings ◽  
Robert F. Meyer ◽  
Ruth M. Corey ◽  
Ann Holmes ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document