THE LDL/APOLIPOPROTEIN B RATIO, AN INDEX FOR LDL PARTICLE SIZE, IS A STRONG PREDICTOR FOR NEOINTIMAL CHARACTERISTICS AND IN-STENT RESTENOSIS AFTER EVEROLIMUS-ELUTING STENT IMPLANTATION

2020 ◽  
Vol 75 (11) ◽  
pp. 1274
Author(s):  
Naotaka Akutsu ◽  
Fukamachi Daisuke ◽  
Yasunari Ebuchi ◽  
Arai Riku ◽  
Suguru Migita ◽  
...  
Keyword(s):  
Particle Size ◽  
Stent Implantation ◽  
Apolipoprotein B ◽  
Strong Predictor ◽  
Ldl Particle Size ◽  
Stent Restenosis ◽  
In Stent Restenosis

Abstract 13420: The LDL/apolipoprotein B Ratio Which is an Index for LDL Particle Size is a Strong Predictor for Neointimal Characteristics and In-stent Restenosis After Everolimus-eluting Stent Implantation

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Naotaka Akutsu ◽  
Riku Arai ◽  
Daisuke Fukamachi ◽  
Yasuo Okumura
Keyword(s):  
Particle Size ◽  
Stent Implantation ◽  
Apolipoprotein B ◽  
Surrogate Marker ◽  
Apo B ◽  
Ldl Particle Size ◽  
Stent Restenosis ◽  
Neointimal Proliferation ◽  
The Impact ◽  
In Stent Restenosis

Introduction: The smaller size of LDL particle has suggested the development of endothelial dysfunction, atherosclerosis and in-stent restenosis (ISR), but little is known regarding the impact of LDL particle size on neointimal formation leading to ISR. Hypothesis: The LDL-C/Apolipoprotein B (Apo B) ratio < 1.2 has been reported to indirectly represent a high proportion of sdLDL. It was hypothesized that in-stent neointimal proliferation in LDL/ApoB < 1.2 patients may be excessive and unstable. Methods: In 135 patients, we investigated the relationship between the LDL particle size and neointimal characteristics using optical coherence tomography (OCT) and coronary angioscopy (CAS) during follow-up angiography after stent implantation. Results: ISR was identified in 35 patients, who had a significantly lower LDL/ApoB ratio (0.99±0.25 vs. 1.17±0.25; p < 0.01) and higher proportion of yellow grade 2 and 3 by CAS than non-ISR group (n=100). Among the non-ISR group, LDL/ApoB < 1.2 group (n=59) had a significantly larger neointimal volume by OCT, and higher proportion of yellow grade 2 and 3 by CAS compared with LDL/ApoB > 1.2 group (n=41) (Figure). Conclusions: Smaller size of LDL strongly associated with the neointimal proliferation, the neointimal instability and ISR evidenced by multimodalities, suggesting that smaller ratio of LDL/ApoB could be a surrogate marker for the neointimal characteristics after stent implantation.

scholarly journals TCTAP A-030 Drug Coated Balloon Versus Drug-eluting Stent for In-stent Restenosis After Drug-eluting Stent Implantation: A Meta-analysis

2021 ◽  
Vol 77 (14) ◽  
pp. S19
Author(s):  
Hendy Bhaskara Perdana Putra ◽  
Quri Meihaerani Savitri ◽  
Wally Wahyu Mukhammad ◽  
Atiyatum Billah ◽  
Alan Dharmasaputra ◽  
...  
Keyword(s):  
Stent Implantation ◽  
Meta Analysis ◽  
Drug Eluting Stent ◽  
Stent Restenosis ◽  
Drug Eluting ◽  
Drug Coated Balloon ◽  
In Stent Restenosis

scholarly journals TCTAP A-083 Impact of Diabetes on Heavily Calcified Plaque in Extremely Late In-stent Restenosis Lesions After Bare-metal Stent Implantation

2014 ◽  
Vol 63 (12) ◽  
pp. S23
Author(s):  
Takahiro Watanabe ◽  
Kazuhiko Yumoto ◽  
Yoshiyasu Takeda ◽  
Yuichi Hanaki ◽  
Yasutoshi Shinoda ◽  
...  
Keyword(s):  
Stent Implantation ◽  
Bare Metal Stent ◽  
Bare Metal ◽  
Metal Stent ◽  
Stent Restenosis ◽  
Calcified Plaque ◽  
In Stent Restenosis

The total apolipoprotein B/LDL-cholesterol ratio does not predict LDL particle size

1995 ◽  
Vol 240 (1) ◽  
pp. 63-73 ◽  
Author(s):  
G.A. Tallis ◽  
M.D.S. Shephard ◽  
S. Sobecki ◽  
M.J. Whiting
Keyword(s):  
Particle Size ◽  
Apolipoprotein B ◽  
Ldl Cholesterol ◽  
Ldl Particle Size ◽  
Cholesterol Ratio

scholarly journals In-Stent Restenosis with "Inflammatory" Neointima Following Everolimus-Eluting Stent Implantation

2018 ◽  
Vol 59 (5) ◽  
pp. 1142-1145 ◽  
Author(s):  
Yumika Tsuji ◽  
Masahiro Koide ◽  
Kanade Katsura ◽  
Hiroshi Fujita ◽  
Hatsue Ishibashi-Ueda ◽  
...  
Keyword(s):  
Stent Implantation ◽  
Stent Restenosis ◽  
In Stent Restenosis

scholarly journals In-Stent Restenosis due to Stent Recoil After Third-Generation Drug-Eluting Stent Implantation

2017 ◽  
Vol 9 (6) ◽  
pp. 534-538 ◽  
Author(s):  
Yuta Kato ◽  
Atsushi Iwata ◽  
Masayuki Nakamura ◽  
Shin-ichiro Miura ◽  
Keijiro Saku
Keyword(s):  
Stent Implantation ◽  
Drug Eluting Stent ◽  
Third Generation ◽  
Stent Restenosis ◽  
Drug Eluting ◽  
In Stent Restenosis

Association of serum procalcitonin level with in-stent restenosis in patients undergoing bare-metal stent implantation

2018 ◽  
Vol 12 (5) ◽  
pp. 455-463 ◽  
Author(s):  
Ender Ornek ◽  
Mustafa Cetin ◽  
Emrullah Kiziltunc ◽  
Alparslan Kurtul ◽  
Murat Gok ◽  
...  
Keyword(s):  
Stent Implantation ◽  
Bare Metal Stent ◽  
Bare Metal ◽  
Metal Stent ◽  
Procalcitonin Level ◽  
Stent Restenosis ◽  
In Stent Restenosis
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