SLV310, a molecule combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition

SLV310, a Novel, Potential Antipsychotic, Combining Potent Dopamine D2 Receptor Antagonism with Serotonin Reuptake Inhibition.

ChemInform ◽

10.1002/chin.200322135 ◽

2003 ◽

Vol 34 (22) ◽

Author(s):

Rolf van Hes ◽

Pieter Smid ◽

Cees N. J. Stroomer ◽

Koos Tipker ◽

Martin Th. M. Tulp ◽

...

Keyword(s):

Serotonin Reuptake ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Antagonism ◽

Dopamine D2 ◽

SLV310, a molecule combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition, active in preclinical models for antipsychotic as well as anxiolytic activity

10.1016/s0924-977x(01)80288-1 ◽

2001 ◽

Vol 11 ◽

pp. S251 ◽

Cited By ~ 3

Author(s):

T. Tuinstra ◽

A.H.J. Herremans ◽

J.A.M. Van der Heyden ◽

A.C. McCreary ◽

M.B. Hesselink ◽

...

Keyword(s):

Serotonin Reuptake ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Anxiolytic Activity ◽

Preclinical Models ◽

Receptor Antagonism ◽

Dopamine D2 ◽

SLV310, a molecule combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition: in vitro and in vivo neurochemistry

10.1016/s0924-977x(02)80481-3 ◽

2002 ◽

Vol 12 ◽

pp. 319

Author(s):

M.B. Hesselink ◽

B. Van Vliet ◽

C.G. Kruse ◽

S.K. Long

Keyword(s):

Serotonin Reuptake ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Antagonism ◽

Dopamine D2 ◽

SLV310, a molecule combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition: In vitro and in vivo neurochemistry

10.1016/s0924-977x(01)80289-3 ◽

2001 ◽

Vol 11 ◽

pp. S252 ◽

Cited By ~ 2

Author(s):

M.B. Hesselink ◽

B. Van Vliet ◽

C.G. Kruse ◽

S.K. Long

Keyword(s):

Serotonin Reuptake ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Antagonism ◽

Dopamine D2 ◽

SLV310, a molecule combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition, active in preclinical models for antipsychotic as well as anxiolytic activity

10.1016/s0924-977x(02)80426-6 ◽

2002 ◽

Vol 12 ◽

pp. 296

Author(s):

T. Tuinstra ◽

A.H.J. Herremans ◽

J.A.M. Van der Heyden ◽

A.C. McCreary ◽

M.B. Hesselink ◽

...

Keyword(s):

Serotonin Reuptake ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Anxiolytic Activity ◽

Preclinical Models ◽

Receptor Antagonism ◽

Dopamine D2 ◽

SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(02)00996-4 ◽

2003 ◽

Vol 13 (3) ◽

pp. 405-408 ◽

Cited By ~ 17

Author(s):

Rolf van Hes ◽

Pieter Smid ◽

Cees N.J Stroomer ◽

Koos Tipker ◽

Martin Th.M Tulp ◽

...

Keyword(s):

Serotonin Reuptake ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Antagonism ◽

Dopamine D2 ◽

Dopamine D2 Receptor Antagonism Suppresses Tau Aggregation and Neurotoxicity

Biological Psychiatry ◽

10.1016/j.biopsych.2012.08.027 ◽

2013 ◽

Vol 73 (5) ◽

pp. 464-471 ◽

Cited By ~ 33

Author(s):

Allyson V. McCormick ◽

Jeanna M. Wheeler ◽

Chris R. Guthrie ◽

Nicole F. Liachko ◽

Brian C. Kraemer

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Antagonism ◽

Dopamine D2 ◽

Tau Aggregation

Long-term perospirone treatment with a single dose at bedtime in schizophrenia: Relevant to intermittent dopamine D2 receptor antagonism

Progress in Neuro-Psychopharmacology and Biological Psychiatry ◽

10.1016/j.pnpbp.2007.10.008 ◽

2008 ◽

Vol 32 (2) ◽

pp. 520-522 ◽

Cited By ~ 3

Author(s):

Ichiro Kusumi ◽

Takuya Masui ◽

Tsukasa Koyama

Keyword(s):

Single Dose ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Antagonism ◽

Dopamine D2

The dopaminergic stabilizers pridopidine (ACR16) and (−)-OSU6162 display dopamine D2 receptor antagonism and fast receptor dissociation properties

European Journal of Pharmacology ◽

10.1016/j.ejphar.2009.11.025 ◽

2010 ◽

Vol 628 (1-3) ◽

pp. 19-26 ◽

Cited By ~ 58

Author(s):

Tino Dyhring ◽

Elsebet Ø. Nielsen ◽

Clas Sonesson ◽

Fredrik Pettersson ◽

Jonas Karlsson ◽

...

Keyword(s):

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Antagonism ◽

Dopamine D2 ◽

Dopaminergic Stabilizers

Mechanism of action of antipsychotic drugs: From dopamine D2 receptor antagonism to glutamate NMDA facilitation

Clinical Therapeutics ◽

10.1016/j.clinthera.2005.07.017 ◽

2005 ◽

Vol 27 ◽

pp. S16-S24 ◽

Cited By ~ 103

Author(s):

Marc Laruelle ◽

W. Gordon Frankle ◽

Rajesh Narendran ◽

Lawrence S. Kegeles ◽

Anissa Abi-Dargham

Keyword(s):

Mechanism Of Action ◽

Antipsychotic Drugs ◽

Dopamine D2 Receptor ◽

D2 Receptor ◽

Receptor Antagonism ◽

Dopamine D2