Clinical safety and activity from a phase 1 study of LOXO-101, a selective TRKA/B/C inhibitor, in solid-tumor patients with NTRK gene fusions

2017 ◽  
Vol 72 ◽  
pp. S148 ◽  
Author(s):  
D.S. Hong ◽  
A. Dowlati ◽  
H.A. Burris ◽  
J.J. Lee ◽  
M.S. Brose ◽  
...  
Keyword(s):  
Solid Tumor ◽  
Phase 1 ◽  
Gene Fusions ◽  
Tumor Patients ◽  
Phase 1 Study ◽  
Clinical Safety

scholarly journals 150O Clinical safety and activity from a phase 1 study of LOXO-101, a selective TRKA/B/C inhibitor, in solid-tumor patients with NTRK gene fusions

2016 ◽  
Vol 27 ◽  
pp. ix46
Author(s):  
D.S. Hong ◽  
A. Dowlati ◽  
H.A. Burris ◽  
J.J. Lee ◽  
M.S. Brose ◽  
...  
Keyword(s):  
Solid Tumor ◽  
Phase 1 ◽  
Gene Fusions ◽  
Tumor Patients ◽  
Phase 1 Study ◽  
Clinical Safety

scholarly journals Phase 1 study of capmatinib in MET‐positive solid tumor patients: Dose escalation and expansion of selected cohorts

2019 ◽  
Vol 111 (2) ◽  
pp. 536-547 ◽  
Author(s):  
Yung‐Jue Bang ◽  
Wu‐Chou Su ◽  
Martin Schuler ◽  
Do‐Hyun Nam ◽  
Wan Teck Lim ◽  
...  
Keyword(s):  
Dose Escalation ◽  
Solid Tumor ◽  
Phase 1 ◽  
Tumor Patients ◽  
Phase 1 Study

scholarly journals Pegylated liposomal mitomycin C prodrug enhances tolerance of mitomycin C: a phase 1 study in advanced solid tumor patients

2015 ◽  
Vol 4 (10) ◽  
pp. 1472-1483 ◽  
Author(s):  
Talia Golan ◽  
Tal Grenader ◽  
Patricia Ohana ◽  
Yasmine Amitay ◽  
Hilary Shmeeda ◽  
...  
Keyword(s):  
Mitomycin C ◽  
Solid Tumor ◽  
Phase 1 ◽  
Advanced Solid Tumor ◽  
Tumor Patients ◽  
Phase 1 Study

Abstract 2675: Biomarker and PK/PD analyses of first in class FASN inhibitor TVB-2640 in a first-in-human phase 1 study in solid tumor patients

2015 ◽  
Author(s):  
Marie O'Farrell ◽  
Richard Crowley ◽  
Timothy S. Heuer ◽  
Doug Buckley ◽  
Chris M. Rubino ◽  
...  
Keyword(s):  
Solid Tumor ◽  
Phase 1 ◽  
Tumor Patients ◽  
Phase 1 Study

Abstract 5337: Phase 1 study of bavituximab in advanced solid tumor malignancies: Final results

2010 ◽  
Author(s):  
Nuhad Ibrahim ◽  
Lucas Wong ◽  
Alison Stopeck ◽  
Lee S. Rosen ◽  
David E. Gerber ◽  
...  
Keyword(s):  
Solid Tumor ◽  
Phase 1 ◽  
Advanced Solid Tumor ◽  
Phase 1 Study

scholarly journals Phase 1 and Pharmacokinetic Study of Intravenous Irinotecan in Refractory Solid Tumor Patients with Hepatic Dysfunction

2006 ◽  
Vol 12 (12) ◽  
pp. 3782-3791 ◽  
Author(s):  
Larry J. Schaaf ◽  
Lisa A. Hammond ◽  
Stuart J. Tipping ◽  
Richard M. Goldberg ◽  
Rakesh Goel ◽  
...  
Keyword(s):  
Pharmacokinetic Study ◽  
Solid Tumor ◽  
Hepatic Dysfunction ◽  
Phase 1 ◽  
Tumor Patients ◽  
Refractory Solid Tumor
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