Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells

2020 ◽  
Vol 83 (8) ◽  
pp. 2518-2527 ◽  
Author(s):  
Chad R. Schultz ◽  
Martin C. H. Gruhlke ◽  
Alan J. Slusarenko ◽  
André S. Bachmann
Keyword(s):  
Ornithine Decarboxylase ◽  
Neuroblastoma Cells ◽  
Decarboxylase Inhibitor

scholarly journals Experimental Fecal Transmission of Human Cryptosporidia to Pigs, and Attempted Treatment with an Ornithine Decarboxylase Inhibitor

1982 ◽  
Vol 19 (6) ◽  
pp. 700-707 ◽  
Author(s):  
H. W. Moon ◽  
A. Schwartz ◽  
M. J. Welch ◽  
P. P. McCann ◽  
P. L. Runnels
Keyword(s):  
Ornithine Decarboxylase ◽  
Potassium Dichromate ◽  
Colonic Epithelium ◽  
Fecal Material ◽  
Decarboxylase Inhibitor ◽  
Apparent Effect ◽  
Newborn Pigs

Fecal material collected from an immunologically deficient man with persistent cryptosporidia infection was stored in potassium dichromate for two weeks and then fed (inoculated) to newborn pigs. The six inoculated newborn pigs shed the organism in their feces starting four to five days after inoculation and continuing for as long as 22 days after inoculation. Pigs which were killed and necropsied while shedding had cryptosporidia infection of ileum, cecum, and colon. Infected pigs had atrophied ileal villi and flattened irregular cecal and colonic epithelium. Uninoculated littermate controls remained free of the infection and had histologically normal intestinal tracts at necropsy. Treatment of three of the six inoculated pigs with the ornithine decarboxylase inhibitor, DL- α-difluoromethylornithine, orally for ten days had no apparent effect on the infection.

Ornithine decarboxylase inhibitor attenuates bombesin enhancement of intestinal carcinogenesis and metastasis induced by azoxymethane

1994 ◽  
Vol 58 (4) ◽  
pp. 533-537 ◽  
Author(s):  
Hiroyasu Iishi ◽  
Masaharu Tatsuta ◽  
Miyako Baba ◽  
Hiroyuki Uehara ◽  
Akihiko Nakaizumi
Keyword(s):  
Ornithine Decarboxylase ◽  
Decarboxylase Inhibitor ◽  
Intestinal Carcinogenesis

scholarly journals Use of the Ornithine Decarboxylase Promoter to Achieve N-MYC-Mediated Overexpression of a Rabbit Carboxylesterase to Sensitize Neuroblastoma Cells to CPT-11

2000 ◽  
Vol 1 (5) ◽  
pp. 457-463 ◽  
Author(s):  
Cynthia A. Pawlik ◽  
Rekha V. Iyengar ◽  
Erik J. Krull ◽  
Stephen E. Mason ◽  
Ruchi Khanna ◽  
...  
Keyword(s):  
Ornithine Decarboxylase ◽  
Neuroblastoma Cells
Sign in / Sign up

Export Citation Format

Share Document