Pyrrolinone-Based HIV Protease Inhibitors. Design, Synthesis, and Antiviral Activity: Evidence for Improved Transport

1995 ◽  
Vol 117 (45) ◽  
pp. 11113-11123 ◽  
Author(s):  
Amos B Smith ◽  
Ralph Hirschmann ◽  
Alexander Pasternak ◽  
Mark C. Guzman ◽  
Akihisa Yokoyama ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors ◽  
Design Synthesis

ChemInform Abstract: Pyrrolinone-Based HIV Protease Inhibitors. Design, Synthesis, and Antiviral Activity: Evidence for Improved Transport.

ChemInform ◽  
2010 ◽  
Vol 27 (13) ◽  
pp. no-no
Author(s):  
A. B. III SMITH ◽  
R. HIRSCHMANN ◽  
A. PASTERNAK ◽  
M. C. GUZMAN ◽  
A. YOKOYAMA ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors ◽  
Design Synthesis

Synthesis, antiviral activity, and bioavailability studies of γ-lactam derived HIV protease inhibitors

1994 ◽  
Vol 2 (9) ◽  
pp. 859-879 ◽  
Author(s):  
Randall W. Hungate ◽  
Jenny L. Chen ◽  
Ken E. Starbuck ◽  
Joseph P. Vacca ◽  
Stacey L. McDaniel ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors

Increased antiviral activity of HIV protease inhibitors of the difluorostatone type bearing (R)-valinol derivatives as novel c-termini

1994 ◽  
Vol 4 (10) ◽  
pp. 1213-1218 ◽  
Author(s):  
V. Van Dorsselaer ◽  
D. Schirlin ◽  
C. Tarnus ◽  
D.L. Taylor ◽  
A.S. Tyms ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors

ChemInform Abstract: Aminodiol HIV Protease Inhibitors. Part 1. Design, Synthesis, and Preliminary SAR.

ChemInform ◽  
2010 ◽  
Vol 25 (44) ◽  
pp. no-no
Author(s):  
J. C. BARRISH ◽  
E. GORDON ◽  
M. ALAM ◽  
P.-F. LIN ◽  
G. S. BISACCHI ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors ◽  
Design Synthesis

Synthesis and antiviral activity of P1′ arylsulfonamide azacyclic urea HIV protease inhibitors

2004 ◽  
Vol 14 (15) ◽  
pp. 4075-4078 ◽  
Author(s):  
Peggy P Huang ◽  
John T Randolph ◽  
Larry L Klein ◽  
Sudthida Vasavanonda ◽  
Tatyana Dekhtyar ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors

Amino Diol HIV Protease Inhibitors. 1. Design, Synthesis, and Preliminary SAR

1994 ◽  
Vol 37 (12) ◽  
pp. 1758-1768 ◽  
Author(s):  
Joel C. Barrish ◽  
Eric Gordon ◽  
Masud Alam ◽  
Pin-Fang Lin ◽  
Gregory S. Bisacchi ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors ◽  
Design Synthesis

Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors

1998 ◽  
Vol 8 (24) ◽  
pp. 3631-3636 ◽  
Author(s):  
Christopher T. Baker ◽  
Francesco G. Salituro ◽  
John J. Court ◽  
David D. Deininger ◽  
Eunice E. Kim ◽  
...  
Keyword(s):  
Conformational Analysis ◽  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors ◽  
Design Synthesis

Synthesis and Antiviral Activity of P1′ Arylsulfonamide Azacyclic Urea HIV Protease Inhibitors.

ChemInform ◽  
2004 ◽  
Vol 35 (49) ◽  
Author(s):  
Peggy P. Huang ◽  
John T. Randolph ◽  
Larry L. Klein ◽  
Sudthida Vasavanonda ◽  
Tatyana Dekhtyar ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors

Design, Synthesis, and Evaluation of Tetrahydropyrimidinones as an Example of a General Approach to Nonpeptide HIV Protease Inhibitors

1997 ◽  
Vol 40 (11) ◽  
pp. 1707-1719 ◽  
Author(s):  
George V. De Lucca ◽  
Jing Liang ◽  
Paul E. Aldrich ◽  
Joe Calabrese ◽  
Beverly Cordova ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Hiv Protease ◽  
Hiv Protease Inhibitors ◽  
Design Synthesis
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