Asymmetric cyclopropanation of allylic ethers: cleavage and regeneration of the chiral auxiliary

1993 ◽  
Vol 58 (4) ◽  
pp. 933-936 ◽  
Author(s):  
Andre B. Charette ◽  
Bernard Cote
2009 ◽  
Vol 20 (9) ◽  
pp. 1065-1072 ◽  
Author(s):  
José M. Vega-Pérez ◽  
Ignacio Periñán ◽  
Fernando Iglesias-Guerra

ChemInform ◽  
2009 ◽  
Vol 40 (24) ◽  
Author(s):  
Debarati Mitra ◽  
Arjun Sengupta ◽  
Kumar Biradha ◽  
Amit Basak

2008 ◽  
Vol 19 (23) ◽  
pp. 2678-2681 ◽  
Author(s):  
Debarati Mitra ◽  
Arjun Sengupta ◽  
Kumar Biradha ◽  
Amit Basak

2021 ◽  
Author(s):  
Jack C. Sharland ◽  
Bo Wei ◽  
David J. Hardee ◽  
Timothy R Hodges ◽  
Wei Gong ◽  
...  

This study describes general methods for the enantioselective syntheses of disubstituted cyclopropane carboxylates including substitution patterns or heterocycle functionality previously observed as significant limitations. The key step is the dirhodium tetracarboxylate-catalyzed asymmetric cyclopropanation of vinyl arenes with aryl- or heteroaryldiazoacetates. The reactions are highly diastereoselective and high asymmetric induction could be achieved using either (<i>R</i>)-pantolactone as a chiral auxiliary or chiral dirhodium tetracarboxylate catalysts.


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