Dynamic Kinetic Resolution-Based Asymmetric Transfer Hydrogenation of 2-Benzoylmorpholinones and Its Use in Concise Stereoselective Synthesis of All Four Stereoisomers of the Antidepressant Reboxetine

Se-Mi Son; Hyeon-Kyu Lee

doi:10.1021/jo401102d

Dynamic Kinetic Resolution-Based Asymmetric Transfer Hydrogenation of 2-Benzoylmorpholinones and Its Use in Concise Stereoselective Synthesis of All Four Stereoisomers of the Antidepressant Reboxetine

The Journal of Organic Chemistry ◽

10.1021/jo401102d ◽

2013 ◽

Vol 78 (17) ◽

pp. 8396-8404 ◽

Cited By ~ 23

Author(s):

Se-Mi Son ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution

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Stereoselective Synthesis of Norephedrine and Norpseudoephedrine by Using Asymmetric Transfer Hydrogenation Accompanied by Dynamic Kinetic Resolution

The Journal of Organic Chemistry ◽

10.1021/jo300867y ◽

2012 ◽

Vol 77 (12) ◽

pp. 5454-5460 ◽

Cited By ~ 36

Author(s):

Hyeon-Kyu Lee ◽

Soyeong Kang ◽

Eun Bok Choi

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution

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Stereoselective Synthesis of 4-Substituted Cyclic Sulfamidate-5-Phosphonates by Using Rh-Catalyzed, Asymmetric Transfer Hydrogenation with Accompanying Dynamic Kinetic Resolution

The Journal of Organic Chemistry ◽

10.1021/acs.joc.5b01434 ◽

2015 ◽

Vol 80 (17) ◽

pp. 8887-8902 ◽

Cited By ~ 12

Author(s):

Yeon Ji Seo ◽

Jin-ah Kim ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution

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Stereoselective synthesis of 4-substituted-cyclic sulfamidate-5-carboxylates by asymmetric transfer hydrogenation accompanied by dynamic kinetic resolution and applications to concise stereoselective syntheses of (−)-epi-cytoxazone and the taxotere side-chain

Chemical Communications ◽

10.1039/c4cc06395c ◽

2014 ◽

Vol 50 (89) ◽

pp. 13706-13709 ◽

Cited By ~ 18

Author(s):

Jin-ah Kim ◽

Yeon Ji Seo ◽

Soyeong Kang ◽

Juae Han ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Side Chain ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution ◽

Stereoselective Syntheses

DKR driven, asymmetric transfer hydrogenations of cyclic sulfamidate imine-5-carboxylates were developed.

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Dynamic kinetic resolution in the stereoselective synthesis of 4,5-diaryl cyclic sulfamidates by using chiral rhodium-catalyzed asymmetric transfer hydrogenation

Chemical Communications ◽

10.1039/c0cc05289b ◽

2011 ◽

Vol 47 (13) ◽

pp. 4004 ◽

Cited By ~ 44

Author(s):

Juae Han ◽

Soyeong Kang ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution

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ChemInform Abstract: Dynamic Kinetic Resolution-Based Asymmetric Transfer Hydrogenation of 2-Benzoylmorpholinones and Its Use in Concise Stereoselective Synthesis of All Four Stereoisomers of the Antidepressant Reboxetine.

ChemInform ◽

10.1002/chin.201405167 ◽

2014 ◽

Vol 45 (5) ◽

pp. no-no

Author(s):

Se-Mi Son ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution

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ChemInform Abstract: Stereoselective Synthesis of 4-Substituted Cyclic Sulfamidate-5-phosphonates by Using Rh-Catalyzed, Asymmetric Transfer Hydrogenation with Accompanying Dynamic Kinetic Resolution.

ChemInform ◽

10.1002/chin.201605153 ◽

2016 ◽

Vol 47 (5) ◽

pp. no-no

Author(s):

Yeon Ji Seo ◽

Jin-ah Kim ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution

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DBU-Promoted Dynamic Kinetic Resolution in Rh-Catalyzed Asymmetric Transfer Hydrogenation of 5-Alkyl Cyclic Sulfamidate Imines: Stereoselective Synthesis of Functionalized 1,2-Amino Alcohols

The Journal of Organic Chemistry ◽

10.1021/acs.joc.8b01892 ◽

2018 ◽

Vol 83 (19) ◽

pp. 11987-11999 ◽

Cited By ~ 8

Author(s):

Hyeong Rae Kim ◽

Raghavendra Achary ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Amino Alcohols ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution

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ChemInform Abstract: Dynamic Kinetic Resolution in the Stereoselective Synthesis of 4,5-Diaryl Cyclic Sulfamidates by Using Chiral Rhodium-Catalyzed Asymmetric Transfer Hydrogenation.

ChemInform ◽

10.1002/chin.201127143 ◽

2011 ◽

Vol 42 (27) ◽

pp. no-no

Author(s):

Juae Han ◽

Soyeong Kang ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution

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ChemInform Abstract: Stereoselective Synthesis of 4-Substituted-Cyclic Sulfamidate-5-carboxylates by Asymmetric Transfer Hydrogenation Accompanied by Dynamic Kinetic Resolution and Applications to Concise Stereoselective Syntheses of (-)-epi-Cytoxazone an

ChemInform ◽

10.1002/chin.201513216 ◽

2015 ◽

Vol 46 (13) ◽

pp. no-no

Author(s):

Jin-ah Kim ◽

Yeon Ji Seo ◽

Soyeong Kang ◽

Juae Han ◽

Hyeon-Kyu Lee

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Asymmetric Transfer Hydrogenation ◽

Dynamic Kinetic Resolution ◽

Stereoselective Syntheses

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Stereoselective Synthesis of syn β-Hydroxy Cycloalkane Carboxylates: Transfer Hydrogenation of Cyclic β-Keto Esters via Dynamic Kinetic Resolution.

ChemInform ◽

10.1002/chin.200746026 ◽

2007 ◽

Vol 38 (46) ◽

Author(s):

Abel Ros ◽

Antonio Magriz ◽

Hansjoerg Dietrich ◽

Jose M. Lassaletta ◽

Rosario Fernandez

Keyword(s):

Kinetic Resolution ◽

Stereoselective Synthesis ◽

Transfer Hydrogenation ◽

Dynamic Kinetic Resolution ◽

Keto Esters

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