Highly Enantioselective Synthesis of Chiral Secondary Amines by Gold(I)/Chiral Brønsted Acid Catalyzed Tandem Intermolecular Hydroamination and Transfer Hydrogenation Reactions

2009 ◽  
Vol 11 (18) ◽  
pp. 4204-4207 ◽  
Author(s):  
Xin-Yuan Liu ◽  
Chi-Ming Che
Keyword(s):  
Enantioselective Synthesis ◽  
Transfer Hydrogenation ◽  
Secondary Amines ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Hydrogenation Reactions ◽  
Acid Catalyzed ◽  
Chiral Bronsted Acid

scholarly journals Chiral Brønsted acid-catalyzed Friedel–Crafts alkylation of electron-rich arenes with in situ-generated ortho-quinone methides: highly enantioselective synthesis of diarylindolylmethanes and triarylmethanes

2015 ◽  
Vol 51 (8) ◽  
pp. 1461-1464 ◽  
Author(s):  
Satyajit Saha ◽  
Santosh Kumar Alamsetti ◽  
Christoph Schneider
Keyword(s):  
Enantioselective Synthesis ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Quinone Methides ◽  
Reaction Conditions ◽  
Brönsted Acid ◽  
Acid Catalyzed ◽  
Chiral Bronsted Acid ◽  
Hydrogen Bonded

Hydrogen-bonded, in situ-generated ortho-quinone methides undergo highly enantioselective Friedel–Crafts reactions with indoles and naphthols under mild reaction conditions.

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