Changes of α 1-protease inhibitor and secretory leukocyte protease inhibitor levels in gingival crevicular fluid before and after non-surgical periodontal treatment

Oral Diseases ◽  
2003 ◽  
Vol 9 (5) ◽  
pp. 249-254 ◽  
Author(s):  
M Nakamura-Minami ◽  
Y Furuichi ◽  
K Ishikawa ◽  
Y Mitsuzono-Tofuku ◽  
Y Izumi
Keyword(s):  
Protease Inhibitor ◽  
Gingival Crevicular Fluid ◽  
Secretory Leukocyte Protease Inhibitor ◽  
Periodontal Treatment ◽  
Before And After ◽  
Crevicular Fluid

scholarly journals Effect of Nonsurgical Periodontal Treatment on Levels of Pyridinoline (ICTP) in the Gingival Crevicular Fluid (GCF)

2017 ◽  
Vol 19 (1) ◽  
pp. 77
Author(s):  
Jorge González Quesada DDS, MSc ◽  
Sonia Rivera Alvarez DDS
Keyword(s):  
Periodontal Disease ◽  
Gingival Crevicular Fluid ◽  
Periodontal Treatment ◽  
Objective Measures ◽  
Good Marker ◽  
Before And After ◽  
Tissue Degradation ◽  
Measures Of Risk ◽  
Student Test ◽  
Crevicular Fluid

The destructive periodontal disease affects the tissues supporting the teeth, with the final result in the loss of it; so the research is directed towards identifying objective measures of risk such as biomarkers of destruction. Because studies of biomarkers present in the gingival crevicular fluid (FGC) have reported promising results, it is posible associated markers of tissue degradation with the progression of periodontal disease. The aim of this study is to determine the effect of nonsurgical periodontal treatment on the levels of pyridinoline in the FGC patients with chronic periodontitis. Materials and Methods: FGC samples (before and after treatment), both active and inactive sites determined by the method of tolerance, ICTP levels were measured using the ICTP EIA. Uni Q, the results were analyzed using Stata 7.0 program and the student-test for nonparametric samples Results: ICTP levels decreased significantly after performing non-surgical periodontal treatment (p = 0.0001). Conclusions: According to the results, the ICTP may be a good marker to monitor the effects of nonsurgical periodontal treatment. 

scholarly journals Effect of Nonsurgical Periodontal Treatment on Levels of Pyridinoline (ICTP) in the Gingival Crevicular Fluid (GCF)

2017 ◽  
Vol 19 (1) ◽  
pp. 77
Author(s):  
Jorge González Quesada DDS, MSc ◽  
Sonia Rivera Alvarez DDS
Keyword(s):  
Periodontal Disease ◽  
Gingival Crevicular Fluid ◽  
Periodontal Treatment ◽  
Objective Measures ◽  
Good Marker ◽  
Before And After ◽  
Tissue Degradation ◽  
Measures Of Risk ◽  
Student Test ◽  
Crevicular Fluid

The destructive periodontal disease affects the tissues supporting the teeth, with the final result in the loss of it; so the research is directed towards identifying objective measures of risk such as biomarkers of destruction. Because studies of biomarkers present in the gingival crevicular fluid (FGC) have reported promising results, it is posible associated markers of tissue degradation with the progression of periodontal disease. The aim of this study is to determine the effect of nonsurgical periodontal treatment on the levels of pyridinoline in the FGC patients with chronic periodontitis. Materials and Methods: FGC samples (before and after treatment), both active and inactive sites determined by the method of tolerance, ICTP levels were measured using the ICTP EIA. Uni Q, the results were analyzed using Stata 7.0 program and the student-test for nonparametric samples Results: ICTP levels decreased significantly after performing non-surgical periodontal treatment (p = 0.0001). Conclusions: According to the results, the ICTP may be a good marker to monitor the effects of nonsurgical periodontal treatment. 

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