Contextual control modes during an airline rescheduling task

Author(s):  
Karen Feigh ◽  
Amy Pritchett ◽  
Tina Denq ◽  
Julie Jacko
Keyword(s):  
2010 ◽  
Vol 43 (1) ◽  
pp. 125-129 ◽  
Author(s):  
Becky L. Nastally ◽  
Mark R. Dixon ◽  
James W. Jackson

2013 ◽  
Vol 118 ◽  
pp. 45-51 ◽  
Author(s):  
L.G. De la Casa ◽  
E. Díaz
Keyword(s):  

2013 ◽  
Vol 27 (11) ◽  
pp. 1023-1031 ◽  
Author(s):  
Amy C Reichelt ◽  
Mark A Good ◽  
Simon Killcross

Previous research demonstrates that disruption of forebrain dopamine systems impairs the use of high-order information to guide goal-directed performance, and that this deficit may be related to impaired use of task-setting cues in patients with schizophrenia. Such deficits can be interrogated through conflict resolution, which has been demonstrated to be sensitive to prefrontal integrity in rodents. We sought to examine the effects of acute systemic d-amphetamine administration on the contextual control of response conflict in rats, and whether deficits were reversed through pre-treatment with clozapine or the D1/D2 antagonist α-flupenthixol. Acute d-amphetamine (1.5 mg/kg) disrupted the utilisation of contextual cues; therefore rats were impaired during presentation of stimulus compounds that require conflict resolution. Evidence suggested that this effect was attenuated through pre-treatment with the atypical antipsychotic clozapine (5.0 mg/kg), but not the typical antipsychotic α-flupenthixol (0.25 mg/kg), at doses previously shown to attenuate d-amphetamine-induced cognitive deficits. These studies therefore demonstrate a potentially viable model of disrupted executive function such as that seen in schizophrenia.


2005 ◽  
Vol 36 (3) ◽  
pp. 297-311 ◽  
Author(s):  
Madonna Murphy ◽  
Darlene M. Skinner

2008 ◽  
Vol 34 (2) ◽  
pp. 223-236 ◽  
Author(s):  
Mark E. Bouton ◽  
Russell J. Frohardt ◽  
Ceyhun Sunsay ◽  
Jaylyn Waddell ◽  
Richard W. Morris

Sign in / Sign up

Export Citation Format

Share Document