Statistical properties of fluctuating enzymes with dynamic cooperativity using a first passage time distribution formalism

2017 ◽  
Vol 146 (14) ◽  
pp. 145103 ◽  
Author(s):  
Divya Singh ◽  
Srabanti Chaudhury
1987 ◽  
Vol 1 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Mark Brown ◽  
Yi-Shi Shao

The spectral approach to first passage time distributions for Markov processes requires knowledge of the eigenvalues and eigenvectors of the infinitesimal generator matrix. We demonstrate that in many cases knowledge of the eigenvalues alone is sufficient to compute the first passage time distribution.


1983 ◽  
Vol 11 (4) ◽  
pp. 1000-1008 ◽  
Author(s):  
Mark Brown ◽  
Narasinga R. Chaganty

1977 ◽  
Vol 14 (4) ◽  
pp. 850-856 ◽  
Author(s):  
Shunsuke Sato

This paper gives an asymptotic evaluation of the probability that the Wiener path first crosses a square root boundary. The result is applied to estimate the moments of the first-passage time distribution of the Ornstein–Uhlenbeck process to a constant boundary.


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