scholarly journals Investigational plasma kallikrein inhibitors for the treatment of diabetic macular edema: an expert assessment

2020 ◽  
Vol 29 (3) ◽  
pp. 237-244 ◽  
Author(s):  
Ashay D. Bhatwadekar ◽  
Viral S. Kansara ◽  
Thomas A. Ciulla
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Expert Assessment ◽  
Plasma Kallikrein ◽  
Kallikrein Inhibitors

Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema

2018 ◽  
Vol 61 (7) ◽  
pp. 2823-2836 ◽  
Author(s):  
Daniel P. Teufel ◽  
Gavin Bennett ◽  
Helen Harrison ◽  
Katerine van Rietschoten ◽  
Silvia Pavan ◽  
...  
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Plasma Kallikrein ◽  
Kallikrein Inhibitors

scholarly journals Plasma Kallikrein-Kinin System as a VEGF-Independent Mediator of Diabetic Macular Edema

Diabetes ◽  
2015 ◽  
Vol 64 (10) ◽  
pp. 3588-3599 ◽  
Author(s):  
Takeshi Kita ◽  
Allen C. Clermont ◽  
Nivetha Murugesan ◽  
Qunfang Zhou ◽  
Kimihiko Fujisawa ◽  
...  
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Plasma Kallikrein ◽  
Kinin System ◽  
Kallikrein Kinin System

scholarly journals Phase 1 Dose-Escalation Study of Plasma Kallikrein Inhibitor THR-149 for the Treatment of Diabetic Macular Edema

2021 ◽  
Vol 10 (14) ◽  
pp. 28
Author(s):  
Pravin U. Dugel ◽  
Arshad M. Khanani ◽  
Brian B. Berger ◽  
Sunil Patel ◽  
Mitchell Fineman ◽  
...  
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Dose Escalation ◽  
Phase 1 ◽  
Plasma Kallikrein ◽  
Dose Escalation Study ◽  
Kallikrein Inhibitor

One-Time Intravitreal Injection of KVD001, a Plasma Kallikrein Inhibitor, in Patients with Central-Involved Diabetic Macular Edema and Reduced Vision

2019 ◽  
Vol 3 (12) ◽  
pp. 1107-1109 ◽  
Author(s):  
Jennifer K. Sun ◽  
Raj K. Maturi ◽  
David S. Boyer ◽  
John A. Wells ◽  
Victor H. Gonzalez ◽  
...  
Keyword(s):  
Macular Edema ◽  
Intravitreal Injection ◽  
Diabetic Macular Edema ◽  
Plasma Kallikrein ◽  
Kallikrein Inhibitor
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