kallikrein inhibitor
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scholarly journals Phase 1 Dose-Escalation Study of Plasma Kallikrein Inhibitor THR-149 for the Treatment of Diabetic Macular Edema

2021 ◽  
Vol 10 (14) ◽  
pp. 28
Author(s):  
Pravin U. Dugel ◽  
Arshad M. Khanani ◽  
Brian B. Berger ◽  
Sunil Patel ◽  
Mitchell Fineman ◽  
...  
Keyword(s):  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Dose Escalation ◽  
Phase 1 ◽  
Plasma Kallikrein ◽  
Dose Escalation Study ◽  
Kallikrein Inhibitor

P051 QLS-215 IS A LONG-ACTING MONOCLONAL ANTIBODY PLASMA KALLIKREIN INHIBITOR FOR THE POTENTIAL TREATMENT OF HAE

2021 ◽  
Vol 127 (5) ◽  
pp. S28
Author(s):  
P. Bista ◽  
A. Nichols ◽  
T. Kiselak ◽  
P. Harwin ◽  
J. Violin ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Plasma Kallikrein ◽  
Potential Treatment ◽  
Kallikrein Inhibitor ◽  
Long Acting

Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE)

2021 ◽  
Vol 64 (17) ◽  
pp. 12453-12468
Author(s):  
Pravin L Kotian ◽  
Minwan Wu ◽  
Satish Vadlakonda ◽  
Venkat Chintareddy ◽  
Pengcheng Lu ◽  
...  
Keyword(s):  
Hereditary Angioedema ◽  
Plasma Kallikrein ◽  
Kallikrein Inhibitor

scholarly journals 579 Rationale and design for the Kallikrein Inhibitor in Netherton Syndrome (KINS) pivotal clinical trial

2020 ◽  
Vol 140 (7) ◽  
pp. S79
Author(s):  
K.W. Johnson ◽  
A. Hovnanian ◽  
J. Teng ◽  
A.S. Paller ◽  
K. Choate ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Kallikrein Inhibitor ◽  
Netherton Syndrome ◽  
Pivotal Clinical Trial

One-Time Intravitreal Injection of KVD001, a Plasma Kallikrein Inhibitor, in Patients with Central-Involved Diabetic Macular Edema and Reduced Vision

2019 ◽  
Vol 3 (12) ◽  
pp. 1107-1109 ◽  
Author(s):  
Jennifer K. Sun ◽  
Raj K. Maturi ◽  
David S. Boyer ◽  
John A. Wells ◽  
Victor H. Gonzalez ◽  
...  
Keyword(s):  
Macular Edema ◽  
Intravitreal Injection ◽  
Diabetic Macular Edema ◽  
Plasma Kallikrein ◽  
Kallikrein Inhibitor

P154 SAFETY AND TOLERABILITY OF ONCE-DAILY ORAL KALLIKREIN INHIBITOR BCX7353 IN PHASE 3 APEX-2 HAE STUDY

2019 ◽  
Vol 123 (5) ◽  
pp. S28-S29
Author(s):  
M. Riedl ◽  
W. Lumry ◽  
A. Banerji ◽  
E. Aygoren-Pursun ◽  
J. Bernstein ◽  
...  
Keyword(s):  
Phase 3 ◽  
Once Daily ◽  
Kallikrein Inhibitor

A review of kallikrein inhibitor lanadelumab in hereditary angioedema

Immunotherapy ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 937-944 ◽  
Author(s):  
Gloria Hwang ◽  
Ansh Johri ◽  
Sally Ng ◽  
Timothy Craig
Keyword(s):  
Hereditary Angioedema ◽  
Kallikrein Inhibitor
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