Cerebral and Spinal Cord Blood Flow in Awake and Fentanyl-N2O Anesthetized Rats

1992 ◽  
Vol 4 (1) ◽  
pp. 31-35 ◽  
Author(s):  
William E. Hoffman ◽  
Christian Werner ◽  
Eberhard Kochs ◽  
Larry Segil ◽  
Guy Edelman ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Blood Flow ◽  
Cord Blood ◽  
Spinal Cord Blood Flow ◽  
Anesthetized Rats

Spinal cord blood flow decreases following microinjection of sodium nitroprusside into the nucleus tractus solitarii of anesthetized rats

1996 ◽  
Vol 25 (3) ◽  
pp. 285-291 ◽  
Author(s):  
Seiji Takao ◽  
Masanobu Maeda ◽  
Masaiwa Inoue ◽  
Takeo Fukushima ◽  
Masamichi Tomonaga ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Blood Flow ◽  
Cord Blood ◽  
Sodium Nitroprusside ◽  
Nucleus Tractus Solitarii ◽  
Spinal Cord Blood Flow ◽  
Anesthetized Rats

Chemical stimulation of the nucleus tractus solitarii decreases spinal cord blood flow in anesthetized rats

1995 ◽  
Vol 185 (2) ◽  
pp. 111-114 ◽  
Author(s):  
Masanobu Maeda ◽  
Masaiwa Inoueaa ◽  
Seiji Takao ◽  
Yoh Ikegami ◽  
Masatsugu Nakai ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Blood Flow ◽  
Cord Blood ◽  
Chemical Stimulation ◽  
Nucleus Tractus Solitarii ◽  
Spinal Cord Blood Flow ◽  
Anesthetized Rats ◽  
Stimulation Of

Microinjection of nitroprusside into the nucleus tractus solitarius decreases spinal cord blood flow in anesthetized rats

1994 ◽  
Vol 19 ◽  
pp. S58
Author(s):  
Seiji Takao ◽  
Masanobu Maeda ◽  
Masaiwa Inoue ◽  
Takeo Fukushima ◽  
Masamichi Tomonaga ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Blood Flow ◽  
Cord Blood ◽  
Nucleus Tractus Solitarius ◽  
Spinal Cord Blood Flow ◽  
Anesthetized Rats

The effect of hypothermia on regional spinal cord blood flow in rats

1989 ◽  
Vol 70 (5) ◽  
pp. 780-784 ◽  
Author(s):  
Toshihisa Sakamoto ◽  
William W. Monafo
Keyword(s):  
Spinal Cord ◽  
Blood Flow ◽  
Cord Blood ◽  
Spinal Cord Ischemia ◽  
Control Level ◽  
Normal Group ◽  
Spinal Cord Blood Flow ◽  
Content Type ◽  
Arterial Blood ◽  
Anesthetized Rats

✓ Spinal cord ischemia may accompany surgical procedures on the aorta or vertebral column. Regional spinal cord blood flow (SCBF) was measured at five vertebral levels in the spinal cords of pentobarbital-anesthetized rats based on the distribution of intravenously injected carbon-14-labeled butanol. In seven normal rats, mean SCBF (± standard error of the mean) ranged from 52.7 ± 5.4 to 68.5 ± 4.9 ml ⋅ min−1 ⋅ 100 gm−1 (depending on the level, being lowest at the thoracic levels) and mean arterial blood pressure (MABP) was 126 mm Hg. Corporal hypothermia (mean rectal temperature 28.1° ± 0.6°C) was induced by cold exposure in seven other rats, and SCBF, measured immediately thereafter, was significantly elevated at all five levels by 52% to 69% compared to the normal group. However, MABP was elevated in the hypothermic group to 165 ± 4 mm Hg (p < 0.0001). Therefore, in seven additional hypothermic rats, MABP was maintained at the control level by withdrawal of arterial blood as necessary. In these animals, SCBF at all levels was still significantly elevated compared with the normal group and the values were nearly identical to those measured in the hypertensive hypothermic rats. It was concluded that hemodynamic autoregulation of SCBF is impaired in the presence of moderate systemic hypothermia in pentobarbital-anesthetized rats.

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