Massive Gastrointestinal Hemorrhage in Systemic Lupus Erythematosus: Successful Treatment With Corticosteroid Pulse Therapy

1999 ◽  
Vol 94 (11) ◽  
pp. 3349-3353 ◽  
Author(s):  
Hideyuki Hiraishi ◽  
Toshiro Konishi ◽  
Shinʼichi Ota ◽  
Tadahito Shimada ◽  
Akira Terano ◽  
...  
Rheumatology ◽  
2000 ◽  
Vol 39 (10) ◽  
pp. 1155-1157 ◽  
Author(s):  
C. Duarte‐Salazar ◽  
J. Cazarín‐Barrientos ◽  
M. V. Goycochea‐Robles ◽  
J. Collazo‐Jaloma ◽  
R. Burgos‐Vargas

2004 ◽  
Vol 59 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Bruno Hollanda Santos ◽  
Rodrigo Ribeiro Santos ◽  
Celeide Fátima Santos ◽  
Adriana Maria Kakehasi ◽  
Hermann Alexandre Vivacqua Von Tiesenhausen

The authors report a case of a 19-year-old woman admitted for the investigation of fever and hemolytic anemia for the previous 2 months. As an inpatient, she had convulsions and sudden loss of consciousness, developing hemoptysis, hypoxia, and respiratory insufficiency. Examination showed pericardial effusions on the echocardiogram and bilateral alveolar condensations on the thoracic radiograph. A hypothetical diagnosis of systemic lupus erythematosus was made, and measurement of the antinuclear factor was requested along with daily pulse therapy methylprednisolone, in spite of which the outcome was fatal. Afterwards, the result of the antinuclear factor test was positive, with a titer of 1:5120, showing a fine punctiform pattern, fulfilling the criteria for systemic lupus erythematosus according to the American College of Rheumatology. Secondary pulmonary hemorrhage in this connective tissue disease is an uncommon but serious complication that involves a high level of mortality in spite of intensive treatment, as is also reported in the literature.


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