scholarly journals Mucosal fixed drug eruption to levetiracetam with early positive patch test on non‐lesional skin

2022 ◽  
Vol 33 (2) ◽  
Author(s):  
Nazli Ercan
Author(s):  
Nazli Ercan

Levetiracetam (LEV) is a second-generation antiepileptic drug (AED) that is well tolerated, has a broad spectrum of action, low protein binding, and minimal hepatic metabolism. The incidence of hypersensitivity to LEV in children and adults is 0.6%. This is the first reported fixed drug eruption (FDE) identified using a patch test in a pediatric case associated with LEV


2016 ◽  
Vol 91 (5) ◽  
pp. 652-654 ◽  
Author(s):  
Aline Soares de Sousa ◽  
José Carlos Cardoso ◽  
Miguel Pinto Gouveia ◽  
Ana Rita Gameiro ◽  
Vera Barreto Teixeira ◽  
...  

2013 ◽  
Vol 41 (3) ◽  
pp. 203-204 ◽  
Author(s):  
L. Sánchez-Morillas ◽  
P. Rojas Pérez-Ezquerra ◽  
M.L. González Morales ◽  
R. González-Mendiola ◽  
J.J. Laguna Martínez

2015 ◽  
Vol 77 (6) ◽  
pp. 579-583 ◽  
Author(s):  
Reiko TOBITA ◽  
Yuko CHINUKI ◽  
Kyoko NOGAMI ◽  
Eishin MORITA

2001 ◽  
Vol 44 (4) ◽  
pp. 246-263 ◽  
Author(s):  
Alexander Rodríguez-Morales ◽  
A. Alonso Llamazares ◽  
R. Palacios Benito ◽  
C. Martínez Cócera

2006 ◽  
Vol 54 (2) ◽  
pp. 127-128 ◽  
Author(s):  
Joan Dalmau ◽  
Esther Serra-Baldrich ◽  
Esther Roe ◽  
Laura Peramiquel ◽  
Agustin Alomar

2001 ◽  
Vol 44 (1) ◽  
pp. 58-58 ◽  
Author(s):  
C. Martín García ◽  
R. Carmena ◽  
R. García ◽  
P. Berges ◽  
E. Camacho ◽  
...  

Author(s):  
Michael Makris ◽  
Christos Fokoloros ◽  
Anna Syrmali ◽  
Zoi Tsakiraki ◽  
Vasileia Damaskou ◽  
...  

Generalized bullous fixed drug eruption (GBFDE) is a specific variant of fixed drug eruption that belongs to severe cutaneous adverse reactions (SCARs) and its diagnosis is based mainly on clinical course and especially on the reoccurrence of typical bullous lesions in previous and new sites after re-administration of the offending drug. We present a well-documented case of fluconazole-induced GBFDE, with a positive patch test to fluconazole (30% weight/volume preparation) and clinical tolerance to itraconazole proven by negative oral provocation. Even in SCARs, patch testing represents a useful diagnostic tool, while oral provocation remains the gold standard in cases that an alternative but the chemically relevant drug must be administered.  


2016 ◽  
Vol 1 (2) ◽  
pp. 1-2
Author(s):  
Mariem Mohamed ◽  
Nadia Nabli ◽  
Saber Zerriaa ◽  
Yosra Soua ◽  
Leila Njim ◽  
...  

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