scholarly journals Generalized Bullous Fixed Drug Eruption to Fluconazole with Positive Patch Testing and Confirmed Tolerance to Itraconazole

2021 ◽  
Author(s):  
Michael Makris ◽  
Christos Fokoloros ◽  
Anna Syrmali ◽  
Zoi Tsakiraki ◽  
Vasileia Damaskou ◽  
...  
Keyword(s):  
Patch Testing ◽  
Drug Eruption ◽  
Adverse Reactions ◽  
Clinical Course ◽  
Fixed Drug Eruption ◽  
Positive Patch Test ◽  
Oral Provocation ◽  
Fixed Drug ◽  
Severe Cutaneous Adverse Reactions ◽  
Cutaneous Adverse Reactions

Generalized bullous fixed drug eruption (GBFDE) is a specific variant of fixed drug eruption that belongs to severe cutaneous adverse reactions (SCARs) and its diagnosis is based mainly on clinical course and especially on the reoccurrence of typical bullous lesions in previous and new sites after re-administration of the offending drug. We present a well-documented case of fluconazole-induced GBFDE, with a positive patch test to fluconazole (30% weight/volume preparation) and clinical tolerance to itraconazole proven by negative oral provocation. Even in SCARs, patch testing represents a useful diagnostic tool, while oral provocation remains the gold standard in cases that an alternative but the chemically relevant drug must be administered.  

Reproducible identification of the causative drug of a fixed drug eruption by oral provocation and lesional patch testing

2002 ◽  
Vol 46 (6) ◽  
pp. 352-353 ◽  
Author(s):  
Sven Zedlitz ◽  
Lars Linzbach ◽  
Roland Kaufmann ◽  
Wolf-Henning Boehncke
Keyword(s):  
Patch Testing ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Oral Provocation ◽  
Causative Drug ◽  
Fixed Drug

scholarly journals Hypersensitivity reactions to folic acid: Three case reports and a review of the literature

2018 ◽  
Vol 32 ◽  
pp. 205873841881770
Author(s):  
Eleonora Nucera ◽  
Arianna Aruanno ◽  
Simona Mezzacappa ◽  
Lucilla Pascolini ◽  
Alessandro Buonomo ◽  
...  
Keyword(s):  
Folic Acid ◽  
Drug Eruption ◽  
Adverse Reactions ◽  
Case Reports ◽  
Hypersensitivity Reactions ◽  
Review Of The Literature ◽  
Fixed Drug Eruption ◽  
The Third ◽  
Fixed Drug ◽  
Uncommon Condition

Adverse reactions to folic acid are an extremely uncommon condition; we present three cases of hypersensitivity to folic acid with different symptomatic manifestations. In the first and second cases, we made the diagnosis of IgE-mediate-type allergy to folic acid, while in the third one, we found a fixed drug eruption to folic acid.

Acebrophylline-induced generalized fixed drug eruption confirmed by an oral provocation test

2017 ◽  
Vol 5 (5) ◽  
pp. 298
Author(s):  
Su Jin Jeong ◽  
Heon Sa-Kong ◽  
Dong-Hee Park ◽  
Sung Geun Lee ◽  
So Young Jung ◽  
...  
Keyword(s):  
Drug Eruption ◽  
Provocation Test ◽  
Fixed Drug Eruption ◽  
Oral Provocation ◽  
Fixed Drug ◽  
Oral Provocation Test

scholarly journals Fixed drug eruption to nimesulide: an exuberant presentation confirmed by patch testing

2018 ◽  
Vol 93 (3) ◽  
pp. 470-472 ◽  
Author(s):  
Lidiane Pereira Marques ◽  
Ana Luiza Castro Fernandes Villarinho ◽  
Maria das Graças Mota Melo ◽  
Marília Gabriela Senra Torre
Keyword(s):  
Patch Testing ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Fixed Drug

scholarly journals Mucosal Fixed Drug Eruption to Levetiracetam with Early Positive Patch Test on Non-Lesional Skin

2021 ◽  
Author(s):  
Nazli Ercan
Keyword(s):  
Patch Test ◽  
Broad Spectrum ◽  
Drug Eruption ◽  
Hepatic Metabolism ◽  
Fixed Drug Eruption ◽  
Pediatric Case ◽  
Lesional Skin ◽  
Positive Patch Test ◽  
Low Protein ◽  
Fixed Drug

Levetiracetam (LEV) is a second-generation antiepileptic drug (AED) that is well tolerated, has a broad spectrum of action, low protein binding, and minimal hepatic metabolism. The incidence of hypersensitivity to LEV in children and adults is 0.6%. This is the first reported fixed drug eruption (FDE) identified using a patch test in a pediatric case associated with LEV

Bullous fixed drug eruption induced by fluconazole: Importance of multi‐site lesional patch testing

2020 ◽  
Author(s):  
Ky Lyn Tan ◽  
Ilaria Bisconti ◽  
Claire Leck ◽  
Thippeswamy Billahalli ◽  
Sheena Barnett ◽  
...  
Keyword(s):  
Patch Testing ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Fixed Drug
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