Solid papillary carcinoma of the breast with an associated Cytokeratin 7- negative Paget's disease of the nipple. Report of a first case

2017 ◽  
Vol 24 (4) ◽  
pp. 637-641 ◽  
Author(s):  
Niels J. Rupp ◽  
Ann-Kathrin Rodewald ◽  
Federica Chiesa ◽  
Zsuzsanna Varga
Keyword(s):  
Papillary Carcinoma ◽  
Paget’S Disease ◽  
Paget's Disease ◽  
Cytokeratin 7 ◽  
Carcinoma Of The Breast ◽  
Solid Papillary Carcinoma ◽  
First Case

Not All Cases of Mammary Paget’s Disease are Cytokeratin-7 Positive: A Challenging Diagnosis!

2021 ◽  
pp. 106689692110029
Author(s):  
Kerschen Anja ◽  
Dano Hélène ◽  
Van Eeckhout Pascal ◽  
Marot Liliane ◽  
Van Bockstal Mieke
Keyword(s):  
Present Report ◽  
Paget’S Disease ◽  
Growth Factor Receptor ◽  
Punch Biopsy ◽  
Paget's Disease ◽  
Cytokeratin 7 ◽  
In Situ Carcinoma ◽  
Epidermal Growth ◽  
Mammary Paget’S Disease

Mammary Paget’s disease accounts for 1% to 3% of all breast tumors and manifests as a chronic eczematous lesion of the areolar skin. It can occur without any underlying neoplasia or can be present in association with an underlying invasive and/or in situ carcinoma of the breast. The present report describes a challenging nipple punch biopsy showing an infiltration of the lower third to two-thirds of the epidermis by large, ovoid, neoplastic cells. The morphology was consistent with mammary Paget's disease, although immunohistochemistry for cytokeratin-7 (CK7) was repeatedly negative. This resulted in an initial misdiagnosis and, subsequently, a delay in the patient's follow-up. Additional immunohistochemistry for GATA binding protein 3 (GATA3) and human epidermal growth factor receptor 2 (HER2), as well as a second opinion of a breast pathologist, resulted in the diagnosis of mammary Paget's disease. The aim of this article is to raise awareness among pathologists and prevent them from misdiagnosing CK7-negative Paget disease of the breast.

scholarly journals Solid papillary carcinoma of the breast

2022 ◽  
Vol 12 ◽  
pp. e2021352
Author(s):  
Toyaja Jadhav ◽  
Shashi Shekhar Prasad ◽  
Bhupesh Guleria ◽  
Manvir Singh Tevatia ◽  
Prerna Guleria
Keyword(s):  
Papillary Carcinoma ◽  
Carcinoma Of The Breast ◽  
Solid Papillary Carcinoma

Solid papillary carcinoma of the breast: A special entity needs to be distinguished from conventional invasive carcinoma avoiding over-treatment

The Breast ◽  
2016 ◽  
Vol 26 ◽  
pp. 67-72 ◽  
Author(s):  
Shuangping Guo ◽  
Yingmei Wang ◽  
Joseph Rohr ◽  
Chaoliang Fan ◽  
Qinglong Li ◽  
...  
Keyword(s):  
Papillary Carcinoma ◽  
Invasive Carcinoma ◽  
Carcinoma Of The Breast ◽  
Solid Papillary Carcinoma

INSM1 immunostaining in solid papillary carcinoma of the breast

2020 ◽  
Author(s):  
Noritaka Kudo ◽  
Jun Takano ◽  
Shinji Kudoh ◽  
Nobuyuki Arima ◽  
Takaaki Ito
Keyword(s):  
Papillary Carcinoma ◽  
Carcinoma Of The Breast ◽  
Solid Papillary Carcinoma

Solid Papillary Carcinoma of the Breast: Report of Two Cases

2001 ◽  
Vol 25 (2) ◽  
pp. 147-152 ◽  
Author(s):  
Chizuko Kanbayashi ◽  
Kuniyuki Oka ◽  
Hando Hakozaki ◽  
Hidetoshi Saito ◽  
Norimasa Sando ◽  
...  
Keyword(s):  
Papillary Carcinoma ◽  
Carcinoma Of The Breast ◽  
Solid Papillary Carcinoma

Cytokeratin 7-negative mammary Paget's disease: A diagnostic pitfall

2016 ◽  
Vol 212 (4) ◽  
pp. 279-281 ◽  
Author(s):  
Ugur Ozerdem ◽  
Jennifer M. McNiff ◽  
Fattaneh A. Tavassoli
Keyword(s):  
Paget’S Disease ◽  
Paget's Disease ◽  
Cytokeratin 7 ◽  
Diagnostic Pitfall ◽  
Mammary Paget’S Disease

Solid?papillary carcinoma of the breast: Clinicopathological study of 20 cases

2007 ◽  
Vol 57 (7) ◽  
pp. 421-429 ◽  
Author(s):  
Yoshiro Otsuki ◽  
Makoto Yamada ◽  
Shin-ichi Shimizu ◽  
Kaori Suwa ◽  
Masayuki Yoshida ◽  
...  
Keyword(s):  
Papillary Carcinoma ◽  
Carcinoma Of The Breast ◽  
Solid Papillary Carcinoma ◽  
Clinicopathological Study
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