scholarly journals RTICBM-74 is a Brain-Penetrant CB1 Receptor Allosteric Modulator that Reduces Alcohol Intake in Rats

2021 ◽  
pp. JPET-AR-2021-000919
Author(s):  
Dennis Lovelock ◽  
Thuy Nguyen ◽  
Kalynn Van Voorhies ◽  
Yanan Zhang ◽  
Joyce Besheer
Keyword(s):  
Alcohol Intake ◽  
Cb1 Receptor ◽  
Allosteric Modulator

scholarly journals A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects

2015 ◽  
Vol 40 (13) ◽  
pp. 2948-2959 ◽  
Author(s):  
Bogna M Ignatowska-Jankowska ◽  
Gemma L Baillie ◽  
Steven Kinsey ◽  
Molly Crowe ◽  
Sudeshna Ghosh ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Cb1 Receptor ◽  
Allosteric Modulator ◽  
Cannabinoid Cb1 Receptor ◽  
Positive Allosteric Modulator ◽  
Psychoactive Effects

scholarly journals In vivo evaluation of the CB1 allosteric modulator LDK1258 reveals CB1-receptor independent behavioral effects

2020 ◽  
Vol 190 ◽  
pp. 172840 ◽  
Author(s):  
Mohammed Mustafa ◽  
Giulia Donvito ◽  
Lauren Moncayo ◽  
Amelia Swafford ◽  
Justin Poklis ◽  
...  
Keyword(s):  
Cb1 Receptor ◽  
Behavioral Effects ◽  
Allosteric Modulator ◽  
In Vivo Evaluation

scholarly journals Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor

2015 ◽  
Vol 172 (20) ◽  
pp. 4790-4805 ◽  
Author(s):  
R B Laprairie ◽  
A M Bagher ◽  
M E M Kelly ◽  
E M Denovan-Wright
Keyword(s):  
Cb1 Receptor ◽  
Allosteric Modulator ◽  
Cannabinoid Cb1 Receptor ◽  
Negative Allosteric Modulator

scholarly journals In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569

2014 ◽  
Vol 25 (2) ◽  
pp. 182-185 ◽  
Author(s):  
Thomas F. Gamage ◽  
Bogna M. Ignatowska-Jankowska ◽  
Jenny L. Wiley ◽  
Mostafa Abdelrahman ◽  
Laurent Trembleau ◽  
...  
Keyword(s):  
Cb1 Receptor ◽  
Allosteric Modulator ◽  
Pharmacological Evaluation
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