Abstract LB-067: Design, synthesis and biological evaluation of novel selenocyanide histone deacetylase inhibitor as anti-triple negative breast cancer agents

2017 ◽  
Author(s):  
Chu Tang ◽  
Yang Du ◽  
Jie Tian
Keyword(s):  
Breast Cancer ◽  
Histone Deacetylase ◽  
Triple Negative Breast Cancer ◽  
Histone Deacetylase Inhibitor ◽  
Triple Negative ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Deacetylase Inhibitor ◽  
Synthesis And Biological Evaluation

scholarly journals Design, synthesis, and biological evaluation of new 6,N2-diaryl-1,3,5-triazine-2,4-diamines as anticancer agents selectively targeting triple negative breast cancer cells

RSC Advances ◽  
2020 ◽  
Vol 10 (43) ◽  
pp. 25517-25528
Author(s):  
Ahmad Junaid ◽  
Felicia Phei Lin Lim ◽  
Edward R. T. Tiekink ◽  
Anton V. Dolzhenko
Keyword(s):  
Breast Cancer ◽  
Triple Negative Breast Cancer ◽  
Anticancer Agents ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
3D Qsar ◽  
Qsar Model ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

New highly potent and selective 6,N2-diaryl-1,3,5-triazine-2,4-diamines were designed and prepared using the 3D-QSAR model developed earlier.

scholarly journals Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat

2012 ◽  
Vol 14 (3) ◽  
Author(s):  
Chandra R Tate ◽  
Lyndsay V Rhodes ◽  
H Chris Segar ◽  
Jennifer L Driver ◽  
F Nell Pounder ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Histone Deacetylase ◽  
Triple Negative Breast Cancer ◽  
Histone Deacetylase Inhibitor ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Deacetylase Inhibitor
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