Abstract 105: Percutaneous Patent Foramen Ovale Closure for the Secondary Prevention of Cryptogenic Cerebral Ischemia: A Network Meta-Analysis

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Georgios Tsivgoulis ◽  
Aristeidis H Katsanos ◽  
Dimitris Mavridis ◽  
Alexandra Frogoudaki ◽  
Agathi-Rosa Vrettou ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Secondary Prevention ◽  
Patent Foramen Ovale ◽  
Meta Analysis ◽  
Foramen Ovale

scholarly journals The Role of Patent Foramen Ovale Closure in the Secondary Prevention of Cryptogenic Stroke: a Meta-Analysis Report

2019 ◽  
Author(s):  
Sónia P. Pinto Pereira ◽  
Alzira Nunes ◽  
Cristina Santos ◽  
Scott E. Kasner ◽  
José P. L. Nunes
Keyword(s):  
Secondary Prevention ◽  
Patent Foramen Ovale ◽  
Meta Analysis ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

Recurrent cerebral ischemia in medically treated patent foramen ovale: A meta-analysis

Neurology ◽  
2009 ◽  
Vol 73 (2) ◽  
pp. 89-97 ◽  
Author(s):  
M. A. Almekhlafi ◽  
S. B. Wilton ◽  
D. M. Rabi ◽  
W. A. Ghali ◽  
D. L. Lorenzetti ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Patent Foramen Ovale ◽  
Meta Analysis ◽  
Foramen Ovale

scholarly journals Comparison of methods for the diagnosis of patent foramen ovale in patients with cryptogenic cerebral ischemia: a meta-analysis

2021 ◽  
Author(s):  
Xiaoxuan Guo ◽  
Xiaojuan Wang ◽  
Lu Zhang ◽  
Yan Zhang ◽  
Rui Peng ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Likelihood Ratio ◽  
Sensitivity And Specificity ◽  
Transthoracic Echocardiography ◽  
Patent Foramen Ovale ◽  
Meta Analysis ◽  
Positive Likelihood Ratio ◽  
Negative Likelihood Ratio ◽  
Receiver Operating Curve ◽  
Foramen Ovale

Background: Foramen ovale is a residual cavity in the developing heart in the fetus. At present, the standard methods for the diagnosis of PFO-right-to-left-shunting (PFO-RLS) include transesophageal echocardiography (TEE), contrast-transcranial Doppler echocardiography (C-TCD), and contrast-transthoracic echocardiography (C-TTE), each of them having its advantages and disadvantages.However, there are no data allowing the comparison of these three methods. Methods: We systematically reviewed all published studies on patients with cryptogenic cerebral ischemia. The sensitivity, specificity, and other indexes of C-TCD and C-TTE in the diagnosis of PFO-RLS were calculated using the Stata 16.0 software. The area under the summary receiver operating curve（SROC) was calculated. Results: Twenty-five 25 controlled studies involving a total of 2282 patients were analyzed. There was considerable heterogeneity between C-TCD and C-TTE sensitivity and specificity among the studies. The combined sensitivity and specificity of C-TCD and C-TTE were 0.95 (95%CI, 0.93-0.97) and 0.86(95%CI, 0.78-0.91), and 0.88 (95%CI, 0.69-0.96) and 0.99 (95%CI, 0.67-1.00). The positive likelihood ratio and negative likelihood ratio of C-TCD and C-TTE were 6.81 (95%CI, 4.42-10.48) and 0.05 (95%CI, 0.03-0.08), and 82.31(95%CI, 2.03-3341.00) and 0.12 (95%CI, 0.04-0.34). The areas under the SROC for C-TCD and C-TTE were 0.97 (95%CI, 0.95–0.98) and 0.98 (95%CI, 0.96–0.99), respectively, and were not significantly different by the Z test (z=-0.17, p=0.86). Conclusion: C-TCD and C-TTE have advantages in diagnosing PFO-RTL. The combination of C-TCD and C-TTE improves the detection rate and reduces the misdiagnosis rate. Key words: patent foramen ovale, cryptogenic cerebral ischemia, contrast-transthoracic echocardiography, contrast-transthoracic echocardiography

Secondary prevention of cryptogenic stroke in patients with patent foramen ovale: a systematic review and meta-analysis

2018 ◽  
Vol 13 (8) ◽  
pp. 1287-1303 ◽  
Author(s):  
Elisa Maria Fiorelli ◽  
Tiziana Carandini ◽  
Delia Gagliardi ◽  
Viviana Bozzano ◽  
Mattia Bonzi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Secondary Prevention ◽  
Patent Foramen Ovale ◽  
Meta Analysis ◽  
Cryptogenic Stroke ◽  
Foramen Ovale

Interventional closure vs. medical therapy of patent foramen ovale for secondary prevention of stroke: updated meta-analysis

2018 ◽  
Vol 108 (2) ◽  
pp. 157-166 ◽  
Author(s):  
Davor Vukadinović ◽  
Stephan H. Schirmer ◽  
Aleksandra Nikolovska Vukadinović ◽  
Christian Ukena ◽  
Bruno Scheller ◽  
...  
Keyword(s):  
Secondary Prevention ◽  
Medical Therapy ◽  
Patent Foramen Ovale ◽  
Meta Analysis ◽  
Foramen Ovale ◽  
Interventional Closure

Secondary Prevention of Cerebral Ischemia in Patent Foramen Ovale

2001 ◽  
Vol 94 (7) ◽  
pp. 699-703 ◽  
Author(s):  
MARISA A. ORGERA ◽  
PATRICK G. OʼMALLEY ◽  
ALLEN J. TAYLOR
Keyword(s):  
Cerebral Ischemia ◽  
Secondary Prevention ◽  
Patent Foramen Ovale ◽  
Foramen Ovale

Secondary Prevention of Cerebral Ischemia in Patent Foramen Ovale

2001 ◽  
Vol 94 (7) ◽  
pp. 699-703 ◽  
Author(s):  
MARISA A. ORGERA ◽  
PATRICK G. OʼMALLEY ◽  
ALLEN J. TAYLOR
Keyword(s):  
Cerebral Ischemia ◽  
Secondary Prevention ◽  
Patent Foramen Ovale ◽  
Foramen Ovale

COMPARISON OF PERCUTANEOUS PATENT FORAMEN OVALE CLOSURE AND MEDICAL THERAPY FOR SECONDARY PREVENTION OF CRYPTOGENIC STROKE: A META-ANALYSIS

2018 ◽  
Vol 71 (11) ◽  
pp. A1287
Author(s):  
Manuel Rivera ◽  
Andrew Panakos ◽  
Kunal Kapoor ◽  
Gilson Fernandes ◽  
Gerardo Zablah ◽  
...  
Keyword(s):  
Secondary Prevention ◽  
Medical Therapy ◽  
Patent Foramen Ovale ◽  
Meta Analysis ◽  
Cryptogenic Stroke ◽  
Foramen Ovale
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