Refractory neuromyelitis optica spectrum disorder in systemic lupus erythematosus successfully treated with rituximab
Keyword(s):
We present a case of a woman with systemic lupus erythematosus (SLE) who had refractory episodes of neuromyelitis optica spectrum disorder (NMOSD) and was successfully treated with rituximab. She was positive for anti-aquaporin-4 (AQP4) antibody and had typical cranial and longitudinally extended spinal lesions but no optic nerve involvement. There is no established treatment for NMOSD/SLE overlap cases. Our experience suggests that rituximab may be effective for patients with combined SLE and anti-AQP4 antibody-positive NMOSD.
2021 ◽
Vol 11
(4)
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pp. 531-535
2020 ◽
Vol 120
(7)
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pp. 102
2019 ◽
Vol 25
(4)
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pp. e38-e40