scholarly journals Plasma plant sterols serve as poor markers of cholesterol absorption in man

2012 ◽  
Vol 54 (4) ◽  
pp. 1144-1150 ◽  
Author(s):  
Lily Jakulj ◽  
Hussein Mohammed ◽  
Theo H. van Dijk ◽  
Theo Boer ◽  
Scott Turner ◽  
...  
2009 ◽  
Vol 154 (4) ◽  
pp. 557-561.e1 ◽  
Author(s):  
Louise S. Merkens ◽  
Julia M. Jordan ◽  
Jennifer A. Penfield ◽  
Dieter Lütjohann ◽  
William E. Connor ◽  
...  

2006 ◽  
Vol 7 (3) ◽  
pp. 450-451
Author(s):  
J.K. Kruit ◽  
T. Plösch ◽  
V.W. Bloks ◽  
N.C.A. Huijkman ◽  
R. Havinga ◽  
...  

1991 ◽  
Vol 40 (S1) ◽  
pp. S59-S63 ◽  
Author(s):  
T. Heinemann ◽  
G. -A. Kullak-Ublick ◽  
B. Pietruck ◽  
K. von Bergmann

1988 ◽  
Vol 174 (2) ◽  
pp. 213-224 ◽  
Author(s):  
M. Vuoristo ◽  
R. Tilvis ◽  
T.A. Miettinen

2007 ◽  
Vol 21 (5) ◽  
Author(s):  
Adrielle H Houweling ◽  
Catherine A Vanstone ◽  
Elke A Trautwein ◽  
Guus SMJE Duchateau ◽  
Peter JH Jones

2003 ◽  
Vol 73 (2) ◽  
pp. 127-134 ◽  
Author(s):  
Miettinen ◽  
Gylling

Normal human diet contains small amounts of phytosterols, mainly sitosterol and campesterol. Intestinal absorption of these plant sterols is low, about one tenth of that of cholesterol, such that their serum concentrations are also low, about 0.1 to 1% of the cholesterol levels. Like cholesterol they are transported by lipoproteins, mainly by LDL, and secreted unchanged in bile. Addition of plant sterols, or especially of their delta-5 saturated derivatives plant stanols into diet as fat-soluble esters inhibit cholesterol absorption and lower serum cholesterol similarly in short-term studies. Long-term consumption of plant stanol esters lowers serum cholesterol to the extent expected to reduce clinical manifestation of coronary heart disease by over 20% without detectable side effecs, cholesterol lowering being especially effective in combination with cholesterol synthesis inhibitors statins.


Circulation ◽  
2004 ◽  
Vol 109 (8) ◽  
pp. 966-971 ◽  
Author(s):  
G. Salen ◽  
K. von Bergmann ◽  
D. Lütjohann ◽  
P. Kwiterovich ◽  
J. Kane ◽  
...  
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