The Effect-Site Concentration of Remifentanil Blunting Cardiovascular Responses to Tracheal Intubation and Skin Incision During Bispectral Index-Guided Propofol Anesthesia

2005 ◽  
Vol 101 (1) ◽  
pp. 125-130 ◽  
Author(s):  
Andrea Albertin ◽  
Andrea Casati ◽  
Lombardo Federica ◽  
Valeri Roberto ◽  
Vittorino Travaglini ◽  
...  
2007 ◽  
Vol 52 (5) ◽  
pp. 521 ◽  
Author(s):  
Hae Kwang Lee ◽  
Byung Hoon Yoo ◽  
Sang Seok Lee ◽  
Yun Hee Lim ◽  
Jun Heum Yon ◽  
...  

2007 ◽  
Vol 53 (5) ◽  
pp. 565 ◽  
Author(s):  
Hong Sik Lee ◽  
Jang-Ho Song ◽  
Helen Ki Shinn ◽  
Jeong Uk Han ◽  
Jong-Kwon Jung ◽  
...  

2002 ◽  
Vol 96 (4) ◽  
pp. 803-816 ◽  
Author(s):  
Michel M. R. F. Struys ◽  
Erik Weber Jensen ◽  
Warren Smith ◽  
N. Ty Smith ◽  
Ira Rampil ◽  
...  

Background Autoregressive modeling with exogenous input of middle-latency auditory evoked potential (A-Line autoregressive index [AAI]) has been proposed for monitoring anesthetic depth. The aim of the current study was to compare the accuracy of this new index with the Bispectral Index (BIS), predicted effect-site concentration of propofol, and hemodynamic measures. Methods Twenty female patients scheduled for ambulatory gynecologic surgery received effect compartment controlled infusion of propofol. Target effect-site concentration was started at 1.5 microg/ml and increased every 4 min by 0.5 microg/ml. At every step, sedation level was compared with monitoring values using different clinical scoring systems and reaction to noxious stimulus. Results Bispectral Index, AAI, and predicted propofol effect-site concentration were accurate indicators for the level of sedation and loss of consciousness. Hemodynamic variables were poor indicators of the hypnotic-anesthetic status of the patient. BIS correlated best with propofol effect-site concentration, followed by AAI. Hemodynamic measurements did not correlate well. No indicators predicted reaction to noxious stimulus. Poststimulus, BIS and AAI showed an increase as a result of arousal. This reaction occurred more rapidly with the AAI than with BIS. Conclusion Bispectral Index, AAI, and predicted propofol effect-site concentration revealed information on the level of sedation and loss of consciousness but did not predict response to noxious stimulus.


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