Particle Characterization of Poorly Water-Soluble Drugs Using a Spray Freeze Drying Technique

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.57.657 ◽

2009 ◽

Vol 57 (7) ◽

pp. 657-662 ◽

Author(s):

Masahiro Kondo ◽

Toshiyuki Niwa ◽

Hirokazu Okamoto ◽

Kazumi Danjo

Keyword(s):

Freeze Drying ◽

Water Soluble ◽

Particle Characterization ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Spray Freeze Drying ◽

Poorly Water Soluble

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Novel Spray Freeze-Drying Technique Using Four-Fluid Nozzle—Development of Organic Solvent System to Expand Its Application to Poorly Water Soluble Drugs

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.58.195 ◽

2010 ◽

Vol 58 (2) ◽

pp. 195-200 ◽

Author(s):

Toshiyuki Niwa ◽

Hiroko Shimabara ◽

Kazumi Danjo

Keyword(s):

Organic Solvent ◽

Freeze Drying ◽

Solvent System ◽

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Spray Freeze Drying ◽

Poorly Water Soluble ◽

Organic Solvent System

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Design of self-dispersible dry nanosuspension through wet milling and spray freeze-drying for poorly water-soluble drugs

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2013.07.011 ◽

2013 ◽

Vol 50 (3-4) ◽

pp. 272-281 ◽

Author(s):

Toshiyuki Niwa ◽

Kazumi Danjo

Keyword(s):

Freeze Drying ◽

Water Soluble ◽

Wet Milling ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Spray Freeze Drying ◽

Poorly Water Soluble

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Characterization of a quaternary liquid system improving the bioavailability of poorly water soluble drugs

Journal of Colloid and Interface Science ◽

10.1016/s0021-9797(03)00321-7 ◽

2003 ◽

Vol 263 (2) ◽

pp. 590-596 ◽

Author(s):

F. Meriani ◽

N. Coceani ◽

C. Sirotti ◽

D. Voinovich ◽

M. Grassi

Keyword(s):

Liquid System ◽

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Characterization of the Precipitates of Poorly Water Soluble Drugs and Determination of the Solubilities in Human Gastro-Intestinal Fluids by Microsopy

Drug Development and Industrial Pharmacy ◽

10.3109/03639049309063005 ◽

1993 ◽

Vol 19 (10) ◽

pp. 1103-1112 ◽

Author(s):

D. M. Simmons

Keyword(s):

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Intestinal Fluids ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Influence of Drug Brittleness, Nanomilling Time, and Freeze-Drying on the Crystallinity of Poorly Water-Soluble Drugs and Its Implications for Solubility Enhancement

AAPS PharmSciTech ◽

10.1208/s12249-017-0722-4 ◽

2017 ◽

Vol 18 (7) ◽

pp. 2437-2445 ◽

Author(s):

Miriam Colombo ◽

Steven Orthmann ◽

Marco Bellini ◽

Sven Staufenbiel ◽

Roland Bodmeier

Keyword(s):

Freeze Drying ◽

Solubility Enhancement ◽

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Development and Characterization of a Biocompatible Soybean Oil-Based Microemulsion for the Delivery of Poorly Water-Soluble Drugs

Journal of Pharmaceutical Sciences ◽

10.1002/jps.24555 ◽

2015 ◽

Vol 104 (10) ◽

pp. 3535-3543 ◽

Author(s):

Carolina Aloisio ◽

Marcela R. Longhi ◽

Anselmo Gomes De Oliveira

Keyword(s):

Soybean Oil ◽

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers

Journal of Pharmacy and Pharmacology ◽

10.1211/0022357011775532 ◽

2001 ◽

Vol 53 (3) ◽

pp. 303-315 ◽

Author(s):

Angus Forster ◽

John Hempenstall ◽

Thomas Rades

Keyword(s):

Amorphous Polymers ◽

Water Soluble ◽

Melt Extrusion ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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In Vitro and In Vivo Characterization of Drug Nanoparticles Prepared Using PureNano™ Continuous Crystallizer to Improve the Bioavailability of Poorly Water Soluble Drugs

Pharmaceutical Research ◽

10.1007/s11095-016-1964-7 ◽

2016 ◽

Vol 33 (9) ◽

pp. 2259-2268 ◽

Author(s):

Kohei Tahara ◽

Masahiro Nishikawa ◽

Ko Matsui ◽

Koji Hisazumi ◽

Risako Onodera ◽

...

Keyword(s):

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Drug Nanoparticles ◽

Water Soluble Drugs ◽

Poorly Water Soluble ◽

In Vivo Characterization

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Characterization of Self-Emulsifying Drug Delivery Systems Using In Situ Raman Spectroscopy to Study the Precipitation Inhibition Mechanism of Poorly Water-Soluble Drugs

Journal of Pharmaceutical Innovation ◽

10.1007/s12247-018-9315-3 ◽

2018 ◽

Vol 13 (2) ◽

pp. 144-154

Author(s):

Shilpa Raut ◽

Eman Atef

Keyword(s):

Water Soluble ◽

Inhibition Mechanism ◽

In Situ Raman Spectroscopy ◽

Poorly Water Soluble Drugs ◽

Precipitation Inhibition ◽

In Situ Raman ◽

Water Soluble Drugs ◽

Poorly Water Soluble

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Dissolution and Solid-State Characterization of Poorly Water-Soluble Drugs in the Presence of a Hydrophilic Carrier

AAPS PharmSciTech ◽

10.1208/s12249-011-9697-8 ◽

2011 ◽

Vol 12 (4) ◽

pp. 1227-1233 ◽

Author(s):

Rahmat Talukder ◽

Chase Reed ◽

Thomas Dürig ◽

Muhammad Hussain

Keyword(s):

Solid State ◽

Water Soluble ◽

Poorly Water Soluble Drugs ◽

Water Soluble Drugs ◽

Poorly Water Soluble ◽

Solid State Characterization

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