scholarly journals A CASE REPORT OF FLORID CLASSICAL PRESENTATION OF SOLITARY PARATHYROID ADENOMA WITH BROWN’S TUMOUR AND HUNGRY BONE SYNDROME

2017 ◽  
Vol 6 (16) ◽  
pp. 1300-1302
Author(s):  
Prerana Bharti ◽  
Dev Raj Sharma ◽  
Ravinder Singh Minhas ◽  
Madhuri Dadwal ◽  
Disha Sharma
Keyword(s):  
Case Report ◽  
Parathyroid Adenoma ◽  
Hungry Bone Syndrome ◽  
Hungry Bone

Hungry bone syndrome after parathyroidectomy caused by an ectopic parathyroid adenoma

2008 ◽  
Vol 27 (1) ◽  
pp. 101-104 ◽  
Author(s):  
Ediz Yeşilkaya ◽  
Peyami Cinaz ◽  
Aysun Bideci ◽  
Orhun Çamurdan ◽  
Fatma Demirel ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Ectopic Parathyroid Adenoma ◽  
Hungry Bone Syndrome ◽  
Ectopic Parathyroid ◽  
Hungry Bone

scholarly journals Fatal Hypocalcaemia Due to Hungry Bone Syndrome with Secondary Refractory HyperParathyroidism after Parathyroidectomy: A Case Report

2019 ◽  
Vol 5 (4) ◽  
pp. 140-144
Author(s):  
Corina Pop Radu ◽  
Valentin Daniealopol ◽  
Ario Santini ◽  
Ruxandra Darie ◽  
Daniela Tatiana Sala
Keyword(s):  
Case Report ◽  
Cardiopulmonary Resuscitation ◽  
Initial Period ◽  
Parathyroid Tissue ◽  
Total Parathyroidectomy ◽  
Cardiac Symptoms ◽  
Hungry Bone Syndrome ◽  
Ionic Calcium ◽  
Hungry Bone ◽  
Secondary Refractory

Abstract Introduction Hungry bone syndrome (HBS) refers to the rapid, profound, and prolonged hypocalcaemia associated with hypophosphatemia and hypomagnesaemia, and is exacerbated by suppressed parathyroid hormone (PTH) levels, which follows parathyroidectomy in patients with severe primary hyperparathyroidism (PHPT) and preoperative high bone turnover. [1] Case report This report concerns a dialysed patient who underwent surgical treatment for secondary refractory hyperparathyroidism. Haemodialysis was carried out pre-operatively, and subsequently, a total parathyroidectomy with auto-transplantation of parathyroid tissue in the sternocleidomastoid muscle (SCM) was performed. Rapid and progressive hypocalcaemia symptoms developed during the second day postoperatively. Acute cardiac symptoms with tachyarrhythmia, haemodynamic instability and finally asystole occurred, which required cardiopulmonary resuscitation (CPR). The ionic calcium level was 2.2 mg/dL being consistent with a diagnosis of HBS. A second cardiac arrest unresponsive to CPR followed an initial period of normal sinus rhythm. Death ensued shortly after. Before death, the ionic calcium was 3.1 mg/dL. Conclusion HBS, after parathyroidectomy in patients with secondary hyperparathyroidism (SHPT), may be severe, prolonged and sometimes fatal. Generally, HBS symptomatology is that of a mild hypocalcaemia. It can, however, include heart rhythm disturbances with haemodynamic alterations requiring intensive care measurements and even cardiopulmonary resuscitation. A close clinical and laboratory post-parathyroidectomy monitoring of dialysed patients is of the utmost importance.

scholarly journals Treatment of hypocalcemia in hungry bone syndrome: A case report

2018 ◽  
Vol 51 ◽  
pp. 335-339 ◽  
Author(s):  
Farahnaz Anwar ◽  
Joseph Abraham ◽  
Ahmad Nakshabandi ◽  
Eugene Lee
Keyword(s):  
Case Report ◽  
Hungry Bone Syndrome ◽  
Hungry Bone

scholarly journals Oxyphil Parathyroid Adenoma Associated with Primary Hyperparathyroidism and Marked Post-Operative Hungry Bone Syndrome.

1996 ◽  
Vol 35 (7) ◽  
pp. 545-549 ◽  
Author(s):  
Koshi NATSUI ◽  
Kiyoshi TANAKA ◽  
Michio SUDA ◽  
Akihiro YASODA ◽  
Chohei SHIGENO ◽  
...  
Keyword(s):  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Hungry Bone Syndrome ◽  
Hungry Bone

Tertiary Hyperparathyroidism

2019 ◽  
Author(s):  
Anna C Beck ◽  
Sonia L Sugg
Keyword(s):  
Renal Transplantation ◽  
Parathyroid Adenoma ◽  
Key Words ◽  
Timing Of Surgery ◽  
Operative Approach ◽  
Parathyroid Hyperplasia ◽  
Tertiary Hyperparathyroidism ◽  
Hungry Bone Syndrome ◽  
Hungry Bone

The definition, pathophysiology, and diagnosis of tertiary hyperparathyroidism is reviewed. Parathyroidectomy is the mainstay of management, and the indications and timing of surgery are explained. The operative approach is described.  This review contains 1 figure, 1 table, and 19 references. Key Words: cinacalcet, hungry bone syndrome, parathyroid adenoma, parathyroidectomy, parathyroid hyperplasia, renal transplantation, tertiary hyperparathyroidism

scholarly journals A case of adolescent giant parathyroid adenoma presenting multiple osteolytic fractures and postoperative hungry bone syndrome

2015 ◽  
Vol 3 (10) ◽  
pp. 835-840 ◽  
Author(s):  
Kosuke Ebina ◽  
Yuji Miyoshi ◽  
Shinji Izumi ◽  
Jun Hashimoto ◽  
Norifumi Naka ◽  
...  
Keyword(s):  
Parathyroid Adenoma ◽  
Hungry Bone Syndrome ◽  
Hungry Bone

scholarly journals Severe Refractory Hypocalcemia After Administering Zoledronic Acid for Osteoporotic Fracture in Primary Hyperparathyroidism That Is Complicated Into Hungry Bone Syndrome: A Case Report

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A221-A222
Author(s):  
Ali Saleh Alhamdan ◽  
Najah Younes Douba ◽  
Abdulaziz Aljamaan ◽  
Abdulrahman Aidh Alghamdi ◽  
Zahrah Abbas Alhammad ◽  
...  
Keyword(s):  
Zoledronic Acid ◽  
Primary Hyperparathyroidism ◽  
Parathyroid Adenoma ◽  
Hip Pain ◽  
Whole Body ◽  
Full Blood Count ◽  
Brown Tumor ◽  
Sudden Drop ◽  
Hungry Bone Syndrome ◽  
Hungry Bone

Abstract Zoledronic acid is a very effective (IV) amino bisphosphonate which is indicated in osteoporosis, hypercalcemia of malignancy, multiple myeloma, Paget’s disease, and bone metastases from solid tumors. Bisphosphonate inhibits bone resorption through actions on osteoclast activity resulting in increasing bone density. Unfortunately, there are side effects associated with zoledronic acid one of those is mild to moderate hypocalcemia. Hungry Bone Syndrome (HBS) is defined as a severe drop in calcium levels less than 2.1 mmol/L and/or prolonged hypocalcemia for more than 4 days post parathyroidectomy. Most seen in patients’ who have secondary hyperparathyroidism compared to primary hyperparathyroidism. The sudden drop of parathyroid (PTH) levels post parathyroid resection after a prolonged duration of high PTH levels causes net calcium to move into the bone, this is the most proposed hypothesis. The authors report a case of a 32 years old female known case of severe osteoporosis presented to the emergency department complaining of left hip pain after a short height fall admitted as a case of pathological fracture. Furthermore, upon admission was vitally stable although on examination the patient had left side hip pain and tenderness otherwise unremarkable. Initial lab investigation showed a calcium level of 2.57 mmol/L and PTH level 37 pmol/L otherwise electrolytes and full blood count were unremarkable. Radiological investigations were done, and an X-ray has shown a left hip fracture where the patient underwent an operating room for fixation. In addition, a 99mTc-HDP bone scan revealed hyperparathyroidism and brown tumor. 99m Tc SESTA-MIBI whole body scan suggested metabolic bone disease. Furthermore, the parathyroid showed suggested typical parathyroid adenoma below and lateral to the lower pole of the left thyroid lobe. The ultrasound of the thyroid showing a well-defined hypoechoic nodule 2.5x1.15 cm with significant hypervascularity is seen, which is most likely to be enlarged left parathyroid gland. Thus, diagnosis of primary hyperparathyroidism has been reached with parathyroid adenoma which was resected during a hospital stay. The patient received pre-op zoledronic acid as a treatment for osteoporosis prior to the hip operation. After the parathyroid adenoma resection, the patient had a sudden drop of PTH and developed hypocalcemia which was 1.1 mmol/L. Thus, the complication of post operated parathyroid adenoma of HBS diagnosis has been made. Interestingly the patient needed to increase the length of stay of the hospital due to refractory hypocalcemia where the patient has been receiving IV calcium and vitamin D supplementation which hadn’t improved until a month of IV calcium gluconate. Although, the patient didn’t develop any signs or symptoms of hypocalcemia.

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