Topical Tranexamic Acid Was Noninferior to Intravenous Tranexamic Acid in Controlling Blood Loss During Total Knee Arthroplasty

2015 ◽  
Vol 97 (4) ◽  
pp. 343 ◽  
Author(s):  
Danyal H. Nawabi
2018 ◽  
Vol 25 (1) ◽  
pp. 73-75 ◽  
Author(s):  
Kwok Pui Pui ◽  
Ho Ka Ki ◽  
Yang Isaac Bruce ◽  
Sha Wai Leung ◽  
Wong Hok Leung ◽  
...  

The objective of this study was to evaluate the efficacy of topical tranexamic acid (TA) on the postoperative blood loss and transfusion rate after primary total knee arthroplasty (TKA). Two hundred ninety-six patients (n = 296) undergoing TKA in Pok Oi Hospital were included in this study from July 2015 to September 2016. The topical TA group (n =154) showed a significant reduction in haemoglobin drop (2.76 g/dL vs. 3.62 g/dL, p < 0.001), haematocrit drop (0.0876 vs. 0.112, p < 0.001), transfusion rate (3.2% vs. 23.9%, p < 0.001), drain output (199 mL vs. 276 mL, p < 0.001) and length of stay (9 days vs. 11 days, p < 0.001) compared with those in the control group (n = 142). There was no thromboembolic complication associated with TA use. The results supported the use of topical TA to control postoperative blood loss after TKA.


2014 ◽  
Vol 22 (2) ◽  
pp. 146-149 ◽  
Author(s):  
Bob Jang ◽  
Mark Kao ◽  
Martin T Bohm ◽  
Ian A Harris ◽  
Darren B Chen ◽  
...  

2014 ◽  
Vol 13 (5) ◽  
pp. 85-88
Author(s):  
Jagadish Surannavar ◽  
◽  
Harsharaj K ◽  
Rajesh s ◽  
Edward Nazareth

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