Leukocytoclastic vasculitis in the facial lesions in cases of mixed connective tissue disease and systemic lupus erythematosus, with a high titer of anti-RNP antibodies.

1985 ◽  
Vol 47 (2) ◽  
pp. 236-241
Author(s):  
Toshio ORIHARA ◽  
Atsuko TSUKADA ◽  
Tatsutaka FURUYA
2021 ◽  
Vol 11 (Number 1) ◽  
pp. 60-65
Author(s):  
Abu Saleh Shimon ◽  
Mahjuba Umme Salam ◽  
Monharul Islam Bhuiyan ◽  
Mashuq Ahmad Jumma ◽  
Imran Hussain ◽  
...  

Mixed connective tissue disease is an entity of autoimmune disease with overlapping features of systemic lupus erythematosus, scleroderma, rheumatoid arthritis, dermatomyositis and with positive anti-U1 RNP antibody. We report here a 52 year old non-diabetic, normotensive woman presenting with new onset dysphagia for two months with variable features of multiple types of connective tissue diseases for two years. Clinical features and type specific serological tests for different connective tissue diseases showed puzzling results. However, finally a high titer of anti-U1RNP antibody led to the diagnosis of mixed connective tissue disease.


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