The study and application of the coordination controller in Web Inspection System (WIS) involves the field of industrial inspection and machine vision technology. The online WIS consists of roller equipment, coordination controller, switch controller, a number of cameras, image management system and management server. Coordination controller based on FPGA design and the LVDS interface, CAN bus interface, is connected through the line with roller equipment, switch controller and a number of camera management server. The CCD camera is connected through the line with image processing systems, and the image processing system connected with management server. Coordinated controller uses a modular design to coordinate control system operation, reduce the CPU load and improve the efficiency of paper defect detection. It is also highly integrated, and able to reduce cabling and costs, so as to raise the efficiency of the controller development, reduce staff workload and improve the working environment.