scholarly journals Optic Disc and Retinal Nerve Fibre Layer Changes in Parkinson’s Disease

2013 ◽  
Vol 37 (1) ◽  
pp. 20-23 ◽  
Author(s):  
Ebru N. Cetin ◽  
Levent S. Bir ◽  
Gülden Sarac ◽  
Filiz Yaldızkaya ◽  
Volkan Yaylalı
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Optic Disc ◽  
Nerve Fibre ◽  
Retinal Nerve Fibre Layer ◽  
Fibre Layer ◽  
Nerve Fibre Layer

scholarly journals Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects

2018 ◽  
Vol 103 (6) ◽  
pp. 821-825 ◽  
Author(s):  
Kunliang Qiu ◽  
Binyao Chen ◽  
Jianling Yang ◽  
Ce Zheng ◽  
Haoyu Chen ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Optic Disc ◽  
Nerve Fibre ◽  
Healthy Subjects ◽  
Retinal Nerve Fibre Layer ◽  
Mean Deviation ◽  
Inner Plexiform Layer ◽  
Retinal Layers ◽  
Fibre Layer ◽  
Nerve Fibre Layer

PurposeTo determine the influence of the optic disc–fovea distance (DFD) on the normative classifications based on thickness measurements of macular inner retinal layers with spectral-domain optical coherence tomography (OCT) in healthy subjects.MethodsA total of 182 eyes from 182 healthy subjects were included (mean (SD) spherical equivalent −0.8 (1.9) dioptres). We performed macula and optic disc imaging with the Topcon 3D OCT 2000. The thickness of the macular inner retinal layers (macular retinal nerve fibre layer (mRNFL), ganglion cell-inner plexiform layer (GCIPL) and both combined (ganglion cell complex; GCC)) and the corresponding classifications based on the built-in normative database were recorded. The occurrence of an abnormal normative classification (occurrence of any thickness variable below the fifth percentile) was related to the DFD and other factors (axial length/refraction, optic disc area, fovea–disc angle, age, gender, image quality, visual field mean deviation and peripapillary retinal nerve fibre layer thickness), using logistic regression.ResultsThe mean (SD) DFD was 4.90 (0.29) mm. A greater DFD was associated with a higher percentage of abnormal normative classification in the OCT parameters describing the thickness of the mRNFL (OR (95%CI) per 0.1 mm increase in DFD: 1.30 (1.13 to 1.50), p<0.001), GCIPL (1.18 (1.02 to 1.38), p=0.023) and GCC measurement (1.29 (1.08 to 1.55), p=0.006).ConclusionsEyes with a greater DFD are prone to false-positive classifications in the thickness assessment of the macular inner retinal layers. The thicknesses should always be interpreted in the context of DFD.

Morphometric evaluation of changes with time in optic disc structure and thickness of retinal nerve fibre layer in chronic ocular hypertensive monkeys

2006 ◽  
Vol 82 (3) ◽  
pp. 427-440 ◽  
Author(s):  
Masamitsu Shimazawa ◽  
Goji Tomita ◽  
Takazumi Taniguchi ◽  
Masaaki Sasaoka ◽  
Hideaki Hara ◽  
...  
Keyword(s):  
Optic Disc ◽  
Nerve Fibre ◽  
Retinal Nerve Fibre Layer ◽  
Fibre Layer ◽  
Nerve Fibre Layer ◽  
Morphometric Evaluation

Relationship between ganglion cell-inner plexiform layer and optic disc/retinal nerve fibre layer parameters in non-glaucomatous eyes

2013 ◽  
Vol 97 (12) ◽  
pp. 1592-1597 ◽  
Author(s):  
Yih-Chung Tham ◽  
Carol Y Cheung ◽  
Victor T Koh ◽  
Ching-Yu Cheng ◽  
Elizabeth Sidhartha ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Optic Disc ◽  
Nerve Fibre ◽  
Plexiform Layer ◽  
Retinal Nerve Fibre Layer ◽  
Inner Plexiform Layer ◽  
Fibre Layer ◽  
Nerve Fibre Layer

scholarly journals Correlation between optic disc topography and retinal nerve fibre layer measurements in glaucoma

2005 ◽  
Vol 83 (3) ◽  
pp. 322-327 ◽  
Author(s):  
Leopoldo Magacho ◽  
Ana M. Marcondes ◽  
Vital P. Costa
Keyword(s):  
Optic Disc ◽  
Nerve Fibre ◽  
Retinal Nerve Fibre Layer ◽  
Fibre Layer ◽  
Nerve Fibre Layer
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