Intracoronary Stent Implantation in Native Coronary Arteries and Saphenous Vein Grafts: A Consecutive Experience With Six Types of Stents Without Prolonged Anticoagulation

1997 ◽  
Vol 72 (2) ◽  
pp. 101-111 ◽  
Author(s):  
Akira Itoh ◽  
Patrick Hall ◽  
Luigi Maiello ◽  
Carlo Di Mario ◽  
Issam Moussa ◽  
...  
2016 ◽  
Vol 23 (8) ◽  
pp. 637-645 ◽  
Author(s):  
Theodor Baars ◽  
Philipp Kahlert ◽  
Albert Baars ◽  
Heike Preibsch ◽  
Tienush Rassaf ◽  
...  

2013 ◽  
Vol 305 (8) ◽  
pp. H1222-H1229 ◽  
Author(s):  
Petra Kleinbongard ◽  
Theodor Baars ◽  
Stefan Möhlenkamp ◽  
Philipp Kahlert ◽  
Raimund Erbel ◽  
...  

Stent implantation into atherosclerotic coronary arteries releases particulate debris and soluble substances that contribute to impaired microvascular perfusion. Here we addressed the potential for microvascular obstruction in patients with stenotic native right coronary arteries (nRCA) compared with saphenous vein grafts on right coronary arteries (SVG-RCA). We enrolled symptomatic, male patients with stable angina pectoris and a flow-limiting stenosis in their nRCA or SVG-RCA ( n = 18/18). Plaque volume and composition were analyzed using intravascular ultrasound before stent implantation. Coronary aspirate was retrieved during stent implantation under protection with a distal occlusion/aspiration device and divided into particulate debris and plasma. The release of catecholamines, endothelin, serotonin, thromboxane B2, and tumor necrosis factor-α was measured. The response of rat mesenteric arteries with intact (+E) and denuded (−E) endothelium to aspirate plasma (without and with selective endothelin receptor blockade) was normalized to that by potassium chloride (KClmax = 100%). Plaque volume and composition were not different between nRCA and SVG-RCA. There was less particulate debris (65 ± 8 vs. 146 ± 23 mg; P < 0.05) and more endothelin release (5.8 ± 0.8 vs. 1.3 ± 0.7 pg/ml; P < 0.05) in nRCA than in SVG-RCA, whereas the release of the other mediators was not different. Aspirate from nRCA induced stronger vasoconstriction than that from SVG-RCA [nRCA, 78 ± 6% (+E)/84 ± 5% (−E); SVG-RCA, 59 ± 6% (+E)/68 ± 3% (−E); P < 0.05 nRCA vs. SVG-RCA], which was attenuated by a nonspecific endothelin and a specific endothelin receptor A antagonist. Thus coronary aspirate from stented nRCA is characterized by less debris but more endothelin and stronger vasoconstrictor response than that from SVG-RCA.


1995 ◽  
Vol 75 (17) ◽  
pp. 1267-1270 ◽  
Author(s):  
Gary S. Mintz ◽  
Jennifer Griffin ◽  
Ya Chien Chuang ◽  
Augusto D. Pichard ◽  
Kenneth M. Kent ◽  
...  

1992 ◽  
Vol 70 (4) ◽  
pp. 449-454 ◽  
Author(s):  
Kirk N. Garratt ◽  
David R. Holmes ◽  
Malcolm R. Bell ◽  
Peter B. Berger ◽  
Urs P. Kaufmann ◽  
...  

2010 ◽  
Vol 55 (10) ◽  
pp. A193.E1808
Author(s):  
Christopher Lichtenwalter ◽  
James A. de Lemos ◽  
Owen Obel ◽  
Abdul-rahman Riyad Abdel-karim ◽  
Michele Roesle ◽  
...  

2009 ◽  
Vol 103 (7) ◽  
pp. 1042-1043 ◽  
Author(s):  
Iñigo Lozano ◽  
Pablo Avanzas ◽  
Juan Rondan

1995 ◽  
Vol 76 (11) ◽  
pp. 822-824 ◽  
Author(s):  
Barry M. Kaplan ◽  
Robert D. Safian ◽  
Cindy L. Grines ◽  
James A. Goldstein ◽  
Dominic L. Marsalese ◽  
...  

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