scholarly journals The Effect of Aging and Severity of Sleep Apnea on Heart Rate Variability Indices in Obstructive Sleep Apnea Syndrome

2012 ◽  
Vol 9 (1) ◽  
pp. 65 ◽  
Author(s):  
Man-Kyu Song ◽  
Jee Hyun Ha ◽  
Seung-Ho Ryu ◽  
Jaehak Yu ◽  
Doo-Heum Park
Keyword(s):  
Heart Rate ◽  
Obstructive Sleep Apnea ◽  
Heart Rate Variability ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Determinants of heart rate variability in obstructive sleep apnea syndrome during wakefulness and sleep

2005 ◽  
Vol 288 (3) ◽  
pp. H1103-H1112 ◽  
Author(s):  
J. A. Jo ◽  
A. Blasi ◽  
E. Valladares ◽  
R. Juarez ◽  
A. Baydur ◽  
...  
Keyword(s):  
Heart Rate ◽  
Obstructive Sleep Apnea ◽  
Heart Rate Variability ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Normal Subjects ◽  
Sinus Arrhythmia ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Heart rate variability (HRV) is mediated by at least three primary mechanisms: 1) vagal feedback from pulmonary stretch receptors (PSR), 2) central medullary coupling between respiratory and cardiovagal neurons (RCC), and 3) arterial baroreflex (ABR)-induced fluctuations. We employed a noninvasive experimental protocol in conjunction with a minimal model to determine how these sources of HRV are altered in obstructive sleep apnea syndrome (OSAS). Respiration, heart rate, and blood pressure were monitored in eight normal subjects and nine untreated OSAS patients in relaxed wakefulness and stage 2 and rapid eye movement sleep. A computer-controlled ventilator delivered inspiratory pressures that varied randomly from breath to breath. Application of the model to the corresponding subject responses allowed the delineation of the three components of HRV. In all states, RCC gain was lower in OSAS patients than in normal subjects ( P < 0.04). ABR gain was also reduced in OSAS patients ( P < 0.03). RCC and ABR gains increased from wakefulness to sleep ( P < 0.04). However, there was no difference in PSR gain between subject groups or across states. The findings of this study suggest that the adverse autonomic effects of OSAS include impairment of baroreflex gain and central respiratory-cardiovascular coupling, but the component of respiratory sinus arrhythmia that is mediated by lung vagal feedback remains intact.

Clinical Implication of Heart Rate Variability in Obstructive Sleep Apnea Syndrome Patients

2015 ◽  
Vol 26 (5) ◽  
pp. 1592-1595 ◽  
Author(s):  
Yoo Suk Kim ◽  
Sung Yul Kim ◽  
Do Yang Park ◽  
Hee Won Wu ◽  
Gyo-Seung Hwang ◽  
...  
Keyword(s):  
Heart Rate ◽  
Obstructive Sleep Apnea ◽  
Heart Rate Variability ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Clinical Implication ◽  
Sleep Apnea Syndrome ◽  
Obstructive Sleep ◽  
Apnea Syndrome

scholarly journals Screening of Obstructive Sleep Apnea Syndrome by Heart Rate Variability Analysis

Circulation ◽  
1999 ◽  
Vol 100 (13) ◽  
pp. 1411-1415 ◽  
Author(s):  
Frédéric Roche ◽  
Jean-Michel Gaspoz ◽  
Isabelle Court-Fortune ◽  
Pascal Minini ◽  
Vincent Pichot ◽  
...  
Keyword(s):  
Heart Rate ◽  
Obstructive Sleep Apnea ◽  
Heart Rate Variability ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Heart Rate Variability Analysis ◽  
Variability Analysis ◽  
Obstructive Sleep ◽  
Apnea Syndrome
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