scholarly journals Cardiac and Sympathetic Activation are Reduced in Children with Down Syndrome and Sleep Disordered Breathing

SLEEP ◽  
2012 ◽  
Author(s):  
Denise M. O’Driscoll ◽  
Rosemary S.C. Horne ◽  
Margot J. Davey ◽  
Sarah A. Hope ◽  
Vicki Anderson ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Sleep Disordered Breathing ◽  
Sympathetic Activation ◽  
Children With Down Syndrome ◽  
Disordered Breathing

Reply to Rana's comment on sleep and sleep disordered breathing in children with Down syndrome

2019 ◽  
Vol 45 ◽  
pp. 135
Author(s):  
Rosemary SC. Horne ◽  
Poornima Wijayaratne ◽  
Gillian M. Nixon ◽  
Lisa M. Walter
Keyword(s):  
Down Syndrome ◽  
Sleep Disordered Breathing ◽  
Children With Down Syndrome ◽  
Disordered Breathing

Treatment and persistence/recurrence of sleep‐disordered breathing in children with Down syndrome

2019 ◽  
Author(s):  
Joy Nehme ◽  
Robert LaBerge ◽  
Mary Pothos ◽  
Nicholas Barrowman ◽  
Lynda Hoey ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Sleep Disordered Breathing ◽  
Children With Down Syndrome ◽  
Disordered Breathing

scholarly journals Night-to-night variation of pulse oximetry in children with sleep-disordered breathing

2016 ◽  
Vol 101 (12) ◽  
pp. 1095-1099 ◽  
Author(s):  
Rachael M Burke ◽  
Barbara Maxwell ◽  
Carolyn Hunter ◽  
David Graham ◽  
Dara O'Donoghue ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Pulse Oximetry ◽  
Sleep Disordered Breathing ◽  
Intraclass Correlation ◽  
Clinical Information ◽  
Children With Down Syndrome ◽  
Statistical Measures ◽  
Overnight Oximetry ◽  
Measured Length ◽  
Disordered Breathing

BackgroundSleep-disordered breathing is a common and serious feature of many paediatric conditions and is particularly a problem in children with Down syndrome. Overnight pulse oximetry is recommended as an initial screening test, but it is unclear how overnight oximetry results should be interpreted and how many nights should be recorded.MethodsThis retrospective observational study evaluated night-to-night variation using statistical measures of repeatability for 214 children referred to a paediatric respiratory clinic, who required overnight oximetry measurements. This included 30 children with Down syndrome. We measured length of adequate trace, basal SpO2, number of desaturations (>4% SpO2 drop for >10 s) per hour (‘adjusted index’) and time with SpO2<90%. We classified oximetry traces into normal or abnormal based on physiology.Results132 out of 214 (62%) children had three technically adequate nights’ oximetry, including 13 out of 30 (43%) children with Down syndrome. Intraclass correlation coefficient for adjusted index was 0.54 (95% CI 0.20 to 0.81) among children with Down syndrome and 0.88 (95% CI 0.84 to 0.91) for children with other diagnoses. Negative predictor value of a negative first night predicting two subsequent negative nights was 0.2 in children with Down syndrome and 0.55 in children with other diagnoses.ConclusionsThere is substantial night-to-night variation in overnight oximetry readings among children in all clinical groups undergoing overnight oximetry. This is a more pronounced problem in children with Down syndrome. Increasing the number of attempted nights’ recording from one to three provides useful additional clinical information.

scholarly journals Sleep phenotype in children with Down syndrome – altered sleep architecture and sleep-disordered breathing

2019 ◽  
Vol 63 (4) ◽  
pp. 179-184
Author(s):  
Romana Gjergja Juraški ◽  
Mirjana Turkalj ◽  
Davor Plavec ◽  
Boro Nogalo ◽  
Ivana Marušić ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Sleep Disordered Breathing ◽  
Sleep Architecture ◽  
Children With Down Syndrome ◽  
Disordered Breathing

Nocturnal dipping of heart rate is impaired in children with Down syndrome and sleep disordered breathing

2021 ◽  
Author(s):  
Ahmad Bassam ◽  
Julie Thacker ◽  
Lisa M. Walter ◽  
Margot J. Davey ◽  
Gillian M. Nixon ◽  
...  
Keyword(s):  
Heart Rate ◽  
Down Syndrome ◽  
Sleep Disordered Breathing ◽  
Children With Down Syndrome ◽  
Nocturnal Dipping ◽  
Disordered Breathing

Sleep disordered breathing in children with Down Syndrome: impact on motor development

2020 ◽  
Author(s):  
Silke Anna Theresa Weber ◽  
Camila Castro Correa ◽  
Karine Silveira Machado ◽  
Deuzilene Costa Sousa ◽  
Leticia Campos
Keyword(s):  
Down Syndrome ◽  
Motor Development ◽  
Sleep Disordered Breathing ◽  
Children With Down Syndrome ◽  
Disordered Breathing
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