Targeting Axonal Transport: A New Therapeutic Avenue for ALS

Amyotrophic Lateral Sclerosis - Recent Advances and Therapeutic Challenges ◽

10.5772/intechopen.91963 ◽

2020 ◽

Author(s):

Wenting Guo ◽

Laura Fumagalli ◽

Ludo Van Den Bosch

Keyword(s):

Axonal Transport ◽

Therapeutic Avenue

Deficient axonal transport of substance P in streptozocin-induced diabetic rats. Effects of sorbinil and insulin

Diabetes ◽

10.2337/diabetes.37.4.488 ◽

1988 ◽

Vol 37 (4) ◽

pp. 488-493 ◽

Cited By ~ 27

Author(s):

D. R. Tomlinson ◽

J. P. Robinson ◽

G. B. Willars ◽

P. Keen

Keyword(s):

Substance P ◽

Axonal Transport ◽

Diabetic Rats

Prevention of defective axonal transport in streptozocin-diabetic rats by treatment with "Statil" (ICI 128436), an aldose reductase inhibitor

Diabetes ◽

10.2337/diabetes.34.10.970 ◽

1985 ◽

Vol 34 (10) ◽

pp. 970-972 ◽

Cited By ~ 18

Author(s):

D. R. Tomlinson ◽

J. Townsend ◽

P. Fretten

Keyword(s):

Axonal Transport ◽

Aldose Reductase ◽

Reductase Inhibitor ◽

Diabetic Rats ◽

Aldose Reductase Inhibitor

Prevention and reversal of defective axonal transport and motor nerve conduction velocity in rats with experimental diabetes by treatment with the aldose reductase inhibitor Sorbinil

Diabetes ◽

10.2337/diabetes.33.5.470 ◽

1984 ◽

Vol 33 (5) ◽

pp. 470-476 ◽

Cited By ~ 46

Author(s):

D. R. Tomlinson ◽

R. J. Moriarty ◽

J. H. Mayer

Keyword(s):

Axonal Transport ◽

Conduction Velocity ◽

Nerve Conduction ◽

Reductase Inhibitor ◽

Nerve Conduction Velocity ◽

Experimental Diabetes ◽

Motor Nerve ◽

Aldose Reductase Inhibitor ◽

Motor Nerve Conduction Velocity ◽

Motor Nerve Conduction

Experimental diabetic neuropathy. Effect of ganglioside treatment on axonal transport of cytoskeletal proteins

Diabetes ◽

10.2337/diabetes.41.7.866 ◽

1992 ◽

Vol 41 (7) ◽

pp. 866-871 ◽

Cited By ~ 5

Author(s):

B. Figliomeni ◽

B. Bacci ◽

C. Panozzo ◽

F. Fogarolo ◽

C. Triban ◽

...

Keyword(s):

Diabetic Neuropathy ◽

Axonal Transport ◽

Cytoskeletal Proteins ◽

Experimental Diabetic Neuropathy

Faculty Opinions recommendation of Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007165.89705 ◽

2002 ◽

Author(s):

Vladimir I Gelfand

Keyword(s):

Axonal Transport ◽

Motor Neurons ◽

Late Onset ◽

Progressive Degeneration

Faculty Opinions recommendation of Kinesin-1/Hsc70-dependent mechanism of slow axonal transport and its relation to fast axonal transport.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1787956.1562054 ◽

2010 ◽

Author(s):

Orly Reiner

Keyword(s):

Axonal Transport ◽

Slow Axonal Transport ◽

Fast Axonal Transport ◽

Dependent Mechanism

Faculty Opinions recommendation of An Arf-like small G protein, ARL-8, promotes the axonal transport of presynaptic cargoes by suppressing vesicle aggregation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4491956.4346054 ◽

2010 ◽

Author(s):

Thomas Melia ◽

Julia Dancourt

Keyword(s):

G Protein ◽

Axonal Transport ◽

Small G Protein

Faculty Opinions recommendation of Vesicular glycolysis provides on-board energy for fast axonal transport.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717976888.793479809 ◽

2013 ◽

Author(s):

Maribel Geli

Keyword(s):

Axonal Transport ◽

Fast Axonal Transport

Faculty Opinions recommendation of Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717990732.793473220 ◽

2013 ◽

Author(s):

Patrick McNutt ◽

Kyle Hubbard

Keyword(s):

Axonal Transport ◽

Motor Neurons ◽

Retrograde Axonal Transport ◽

Botulinum Neurotoxins

Faculty Opinions recommendation of β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717992197.793477132 ◽

2013 ◽

Author(s):

Elias Spiliotis

Keyword(s):

Axonal Transport ◽

Tubulin Mutations ◽

Β Tubulin