Live-attenuated Tetravalent Dengue Vaccine in Dengue-naïve Children, Adolescents, and Adults in Mexico City

2011 ◽  
Vol 30 (1) ◽  
pp. e9-e17 ◽  
Author(s):  
Jorge Poo ◽  
Francisco Galan ◽  
Remi Forrat ◽  
Betzana Zambrano ◽  
Jean Lang ◽  
...  
Keyword(s):  
Mexico City ◽  
Dengue Vaccine ◽  
Adolescents And Adults

scholarly journals Exposure to PM2.5 and Obesity Prevalence in the Greater Mexico City Area

2021 ◽  
Vol 18 (5) ◽  
pp. 2301
Author(s):  
Marcela Tamayo-Ortiz ◽  
Martha María Téllez-Rojo ◽  
Stephen J. Rothenberg ◽  
Ivan Gutiérrez-Avila ◽  
Allan Carpenter Just ◽  
...  
Keyword(s):  
Mexico City ◽  
Latin American ◽  
Meta Analysis ◽  
Obesity Prevalence ◽  
Logistic Regression Models ◽  
City Area ◽  
Adolescents And Adults ◽  
Pm2.5 Exposure ◽  
Greater Mexico ◽  
Adjusted Logistic Regression

Exposure to PM2.5 has been associated with the prevalence of obesity. In the Greater Mexico City Area (GMCA), both are ranked among the highest in the world. Our aim was to analyze this association in children, adolescents, and adults in the GMCA. We used data from the 2006 and 2012 Mexican National Surveys of Health and Nutrition (ENSANUT). Participants’ past-year exposure to ambient PM2.5 was assessed using land use terms and satellite-derived aerosol optical depth estimates; weight and height were measured. We used survey-adjusted logistic regression models to estimate the odds ratios (ORs) of obesity (vs. normal-overweight) for every 10 µg/m3 increase in annual PM2.5 exposure for children, adolescents, and adults. Using a meta-analysis approach, we estimated the overall odds of obesity. We analyzed data representing 19.3 million and 20.9 million GMCA individuals from ENSANUT 2006 and 2012, respectively. The overall pooled estimate between PM2.5 exposure and obesity was OR = 1.96 (95% CI: 1.21, 3.18). For adolescents, a 10 µg/m3 increase in PM2.5 was associated with an OR of 3.53 (95% CI: 1.45, 8.58) and 3.79 (95% CI: 1.40, 10.24) in 2006 and 2012, respectively. More studies such as this are recommended in Latin American cities with similar air pollution and obesity conditions.

scholarly journals Dengue Vaccine Booster in Healthy Adolescents and Adults in Latin America

2019 ◽  
Vol 38 (5) ◽  
pp. e90-e95 ◽  
Author(s):  
Diana Coronel ◽  
Enid J. García-Rivera ◽  
Maribel Rivera ◽  
José Luis Arredondo-García ◽  
Reynaldo Dietze ◽  
...  
Keyword(s):  
Latin America ◽  
Dengue Vaccine ◽  
Vaccine Booster ◽  
Adolescents And Adults

scholarly journals Immunogenicity and safety of a tetravalent dengue vaccine in dengue-naïve adolescents in Mexico City

2021 ◽  
Vol 45 ◽  
pp. 1
Author(s):  
Shibadas Biswal ◽  
Jorge Fernando Mendez Galvan ◽  
Mercedes Macias Parra ◽  
Juan-Francisco Galan-Herrera ◽  
Monica Belisa Carrascal Rodriguez ◽  
...  
Keyword(s):  
Adverse Events ◽  
Injection Site ◽  
Mexico City ◽  
Neutralizing Antibodies ◽  
Geometric Mean ◽  
Dengue Vaccine ◽  
Microneutralization Assay ◽  
To Receive

Objective. To describe the immunogenicity and safety of a tetravalent dengue vaccine (TAK-003) in healthy adolescents living in Mexico City, an area considered non-endemic for dengue (NCT03341637). Methods. Participants aged 12–17 years were randomized 3:1 to receive two doses (Month 0 and Month 3) of TAK-003 or placebo. Immunogenicity was assessed by microneutralization assay of dengue neutralizing antibodies at baseline, Months 4 and 9. Solicited and unsolicited adverse events (AEs) were recorded after each vaccination. Serious (SAEs) and medically-attended AEs (MAAEs) were recorded throughout the study. Results. 400 adolescents were enrolled, 391 (97.8%) completed the study. Thirty-six (9%) were baseline seropositive to ≥1 serotypes (reciprocal titer ≥10). Geometric mean titers (GMTs) in baseline seronegative TAK-003 recipients were 328, 1743, 120, and 143 at Month 4, and 135, 741, 46, and 38 at Month 9 against DENV-1, -2, -3, and -4, respectively. Placebo GMTs remained <10. Tetravalent seropositivity rates in vaccine recipients were 99.6% and 85.8% at Months 4 and 9, respectively. One MAAE in each group was considered treatment-related (TAK-003: injection-site erythema, and placebo: pharyngitis). Conclusion. TAK-003 was immunogenic against all four serotypes and was well tolerated in dengue-naïve adolescents living in Mexico City.

scholarly journals Colours, capsules and concept flavour names on cigarette packs appeal to youth in Mexico

2022 ◽  
pp. tobaccocontrol-2021-056905
Author(s):  
Jennifer L Brown ◽  
Graziele Grilo ◽  
Joanna E Cohen ◽  
Katherine Clegg Smith ◽  
Luz Myriam Reynales-Shigematsu ◽  
...  
Keyword(s):  
Mexico City ◽  
Conditional Logistic Regression ◽  
Mixed Effects ◽  
Design Features ◽  
Packaging Design ◽  
Adolescents And Adults ◽  
Influence Perceptions ◽  
Perceived Harm ◽  
Cigarette Packs ◽  
Experimental Survey

BackgroundFlavoured cigarettes are popular in Mexico. We examined how cigarette packaging design features used to communicate flavour influence perceptions of appeal, harm, perceived interest and pack preference among Mexico City residents.MethodsWe conducted an experimental survey. Participants aged 13–34 years were randomly assigned to one of three conditions, viewed packs with systematically manipulated design features (colour, capsule image and flavour name) and answered questions on appeal, perceived harm, perceived interest and pack preference. Data were analysed using mixed effects and conditional logistic regression.Results1500 adolescents and 950 adults participated. Regardless of flavour, cigarette packs with a background colour and capsule image were more appealing to adolescents (OR=13.19, 95% CI 11.53 to 15.10; OR=1.68, 95% CI 1.45 to 1.88) and adults (OR=4.18, 95% CI 3.73 to 4.69; OR=1.66, 95% CI 1.49 to 1.85) than packs without. Among adolescents, ‘Tropical Burst’ named packs were more appealing (OR=1.43, 95% CI 1.20 to 1.72) than packs without a flavour name and among adults, ‘Arctic Air’ named packs were more appealing (OR=1.20, 95% CI 1.02 to 1.14). Adolescents and adults reported a preference for trying packs that displayed a flavour name, background colour or capsule image (b=0.104, b=0.702, b=1.316, p<0.001 and b=0.126, b=0.619, b=0.775, p<0.001).ConclusionsColours and flavour capsule images appeal to adolescents and adults in Mexico. Mexico should consider adopting plain packaging to reduce appeal and interest.

Live-attenuated, tetravalent dengue vaccine in children, adolescents and adults in a dengue endemic country: Randomized controlled phase I trial in the Philippines

Vaccine ◽  
2011 ◽  
Vol 29 (22) ◽  
pp. 3863-3872 ◽  
Author(s):  
Rosario Z. Capeding ◽  
Imelda A. Luna ◽  
Emily Bomasang ◽  
Socorro Lupisan ◽  
Jean Lang ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Trial ◽  
The Philippines ◽  
Endemic Country ◽  
Dengue Vaccine ◽  
Randomized Controlled ◽  
Adolescents And Adults

Clinical Success Using the Audio-Visual Feedback Training for Cluttering

2019 ◽  
Vol 4 (6) ◽  
pp. 1589-1594
Author(s):  
Yvonne van Zaalen ◽  
Isabella Reichel
Keyword(s):  
Visual Feedback ◽  
Clinical Success ◽  
Pause Duration ◽  
Digital Audio ◽  
Male Adolescents ◽  
Feedback Training ◽  
Positive Effects ◽  
Speech Monitoring ◽  
Adolescents And Adults

Purpose Among the best strategies to address inadequate speech monitoring skills and other parameters of communication in people with cluttering (PWC) is the relatively new but very promising auditory–visual feedback (AVF) training ( van Zaalen & Reichel, 2015 ). This study examines the effects of AVF training on articulatory accuracy, pause duration, frequency, and type of disfluencies of PWC, as well as on the emotional and cognitive aspects that may be present in clients with this communication disorder ( Reichel, 2010 ; van Zaalen & Reichel, 2015 ). Methods In this study, 12 male adolescents and adults—6 with phonological and 6 with syntactic cluttering—were provided with weekly AVF training for 12 weeks, with a 3-month follow-up. Data was gathered on baseline (T0), Week 6 (T1), Week 12 (T2), and after follow-up (T3). Spontaneous speech was recorded and analyzed by using digital audio-recording and speech analysis software known as Praat ( Boersma & Weenink, 2017 ). Results The results of this study indicated that PWC demonstrated significant improvements in articulatory rate measurements and in pause duration following the AVF training. In addition, the PWC in the study reported positive effects on their ability to retell a story and to speak in more complete sentences. PWC felt better about formulating their ideas and were more satisfied with their interactions with people around them. Conclusions The AVF training was found to be an effective approach for improving monitoring skills of PWC with both quantitative and qualitative benefits in the behavioral, cognitive, emotional, and social domains of communication.

Allergic Reactions to Food Proteins

2011 ◽  
Vol 81 (23) ◽  
pp. 173-180 ◽  
Author(s):  
Barbara K. Ballmer-Weber
Keyword(s):  
Food Allergies ◽  
Allergic Reactions ◽  
Allergenic Food ◽  
Processed Foods ◽  
Legal Regulations ◽  
Pollen Allergens ◽  
Curative Therapy ◽  
Novel Foods ◽  
Allergenic Proteins ◽  
Adolescents And Adults

Four to eight percent of the population are estimated to be food-allergic. Most food allergies in adolescents and adults are acquired on the basis of cross-reaction to pollen allergens. Theses allergens are ubiquitous in the plant kingdom. Therefore pollen-allergic patients might acquire a multitude of different plant food allergies, and even react to novel foods to which they have never previously been exposed. A curative therapy for food allergy does not yet exist. Food-allergic patients have to rely on strict avoidance diets, The widespread use of industrially processed foods poses a general problem for food-allergic patients. Although the most frequent allergens must be declared openly in the list of ingredients, involuntary contamination with allergy-provoking compounds can occur. The precautionary labelling “may contain” is sometimes applied even if the chance of contamination is very low; on the other hand, foods not declared to contain possible traces of allergenic components may actually contain relevant amounts of allergenic proteins. Switzerland is the only country in Europe with legal regulations on contamination by allergenic food; however, the allowance of 1 g/kg is too high to protect a relevant proportion of food-allergic individuals.

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