Boosted Weighted Optimized Convolutional Neural Network Ensemble Classification for Lung Cancer Prediction

One of the major causes of cancer-related mortality worldwide is lung tumors. An earlier prediction of lung tumors is crucial since it may severely increase the death rates. For this reason, genomic profiles have been considered in many advanced microarray technology schemes. Amongst, an Improved Dragonfly optimization Algorithm (IDA) with Boosted Weighted Optimized Neural Network Ensemble Classification (BWONNEC) has been developed which extracts most suitable features and fine-tunes the weights related to the ensemble neural network classifiers. But, its major limitations are the number of learning factors in neural network and computational difficulty. Therefore in this article, a Boosted Weighted Optimized Convolutional Neural Network Ensemble Classification (BWOCNNEC) algorithm is proposed to lessen the number of learning factors and computation cost of neural network. In this algorithm, the boosting weights are combined into the CNN depending on the least square fitness value. Then, the novel weight values are assigned to the features extracted by the IDA. Moreover, these weight values and the chosen features are processed in different CNN structures within the boosted classifier. Further, the best CNN structure in each iteration i.e., CNNs having the least weighted loss is selected and ensemble to predict and diagnose the lung tumors effectively. Finally, the investigational outcomes exhibit that the IDA-BWOCNNEC achieves better prediction efficiency than the existing algorithms.

Comparison of Multivariable Logistic Regression and Machine Learning Models for Predicting Bronchopulmonary Dysplasia or Death in Very Preterm Infants

Bronchopulmonary dysplasia (BPD) is the most prevalent and clinically significant complication of prematurity. Accurate identification of at-risk infants would enable ongoing intervention to improve outcomes. Although postnatal exposures are known to affect an infant's likelihood of developing BPD, most existing BPD prediction models do not allow risk to be evaluated at different time points, and/or are not suitable for use in ethno-diverse populations. A comprehensive approach to developing clinical prediction models avoids assumptions as to which method will yield the optimal results by testing multiple algorithms/models. We compared the performance of machine learning and logistic regression models in predicting BPD/death. Our main cohort included infants <33 weeks' gestational age (GA) admitted to a Canadian Neonatal Network site from 2016 to 2018 (n = 9,006) with all analyses repeated for the <29 weeks' GA subcohort (n = 4,246). Models were developed to predict, on days 1, 7, and 14 of admission to neonatal intensive care, the composite outcome of BPD/death prior to discharge. Ten-fold cross-validation and a 20% hold-out sample were used to measure area under the curve (AUC). Calibration intercepts and slopes were estimated by regressing the outcome on the log-odds of the predicted probabilities. The model AUCs ranged from 0.811 to 0.886. Model discrimination was lower in the <29 weeks' GA subcohort (AUCs 0.699–0.790). Several machine learning models had a suboptimal calibration intercept and/or slope (k-nearest neighbor, random forest, artificial neural network, stacking neural network ensemble). The top-performing algorithms will be used to develop multinomial models and an online risk estimator for predicting BPD severity and death that does not require information on ethnicity.

Classifying chest CT images as COVID-19 positive/negative using a convolutional neural network ensemble model and uniform experimental design method

Background To classify chest computed tomography (CT) images as positive or negative for coronavirus disease 2019 (COVID-19) quickly and accurately, researchers attempted to develop effective models by using medical images. Results A convolutional neural network (CNN) ensemble model was developed for classifying chest CT images as positive or negative for COVID-19. To classify chest CT images acquired from COVID-19 patients, the proposed COVID19-CNN ensemble model combines the use of multiple trained CNN models with a majority voting strategy. The CNN models were trained to classify chest CT images by transfer learning from well-known pre-trained CNN models and by applying their algorithm hyperparameters as appropriate. The combination of algorithm hyperparameters for a pre-trained CNN model was determined by uniform experimental design. The chest CT images (405 from COVID-19 patients and 397 from healthy patients) used for training and performance testing of the COVID19-CNN ensemble model were obtained from an earlier study by Hu in 2020. Experiments showed that, the COVID19-CNN ensemble model achieved 96.7% accuracy in classifying CT images as COVID-19 positive or negative, which was superior to the accuracies obtained by the individual trained CNN models. Other performance measures (i.e., precision, recall, specificity, and F1-score) obtained bythe COVID19-CNN ensemble model were higher than those obtained by individual trained CNN models. Conclusions The COVID19-CNN ensemble model had superior accuracy and excellent capability in classifying chest CT images as COVID-19 positive or negative.

Performance based Evaluation ofAlgorithmson Chronic Kidney Disease using Hybrid Ensemble Model in Machine Learning

In medical data science, data classification, pattern generation, data analysis and improving classification accuracy are the important issues in the recent scenario. The main objective of this research to enhanced classification accuracyby four combinations of features technique separately with Neural Network classifier approach.The neural network is analyzed for chronic kidney disease with the help of features reduction and relevanttechniques.In experiment, we used neural network as ensemble model with different features techniques as: Pearson Correlation, Chi-Square, Extra Tree and Lasso regularization. In this research paper, we have prepared training model on 300(75%) instances of chronic kidney disease attributes and testing on 100 (25%) instances.We test the dataset on different applied epochs and calculated accuracy with error rate. The summary of this experiment, we used400 instances with 26 attributes of Chronic Kidney Disease and evaluated highest accuracy calculated (99.98%) with less error rate on passing several epochs by Neural Network ensemble with Lasso model.