Asymmetric Metal-Catalyzed 1,3-Dipolar Cycloaddition Reactions

Author(s):  
Kurt Vesterager Gothelf
2020 ◽  
Vol 23 (27) ◽  
pp. 3064-3134 ◽  
Author(s):  
Ana L. Cardoso ◽  
Maria I.L. Soares

The 1,3-dipolar cycloaddition reaction is a powerful and versatile strategy for the synthesis of carbocyclic and heterocyclic five-membered rings. Herein, the most recent developments on the [3+2] cycloaddition reactions using allenes acting either as dipolarophiles or 1,3-dipole precursors, are highlighted. The recent contributions on the phosphine- and transition metal-catalyzed [3+2] annulations involving allenes as substrates are also covered, with the exception of those in which the formation of a 1,3-dipole (or synthetic equivalent) is not invoked. This review summarizes the most relevant research in which allenes are used as building blocks for the construction of structurally diverse five-membered rings via [3+2] annulation reactions.


2018 ◽  
Vol 16 (44) ◽  
pp. 8446-8461 ◽  
Author(s):  
Silvia Roscales ◽  
Joaquín Plumet

In this review recent advances in the metal-catalyzed 1,3-dipolar cycloaddition reactions of nitrile oxides are highlighted, covering references from the period 2000 until August 2018.


1996 ◽  
Vol 50 ◽  
pp. 652-660 ◽  
Author(s):  
Kurt V. Gothelf ◽  
Karl Anker Jørgensen ◽  
Carl E. Olsen ◽  
Birgitte R. Rassing ◽  
Jo Klaveness ◽  
...  

2013 ◽  
Vol 17 (18) ◽  
pp. 1929-1956 ◽  
Author(s):  
Natarajan Arumugam ◽  
Raju Kumar ◽  
Abdulrahman Almansour ◽  
Subbu Perumal

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