Supramolecularly Regulated Enantioselective Catalysts

2021 ◽  
pp. 591-603
Author(s):  
Anton Vidal‐Ferran
Keyword(s):  
Enantioselective Catalysts

Enantioselective Michael Addition of Malonates to Enones

2020 ◽  
Vol 24 (7) ◽  
pp. 746-773
Author(s):  
Péter Bakó ◽  
Tamás Nemcsok ◽  
Zsolt Rapi ◽  
György Keglevich
Keyword(s):  
Michael Addition ◽  
Activity Relationship ◽  
Chalcone Derivatives ◽  
Michael Additions ◽  
Michael Reactions ◽  
Structure Activity ◽  
Cyclic Enones ◽  
Michael Acceptors ◽  
Relationship Of ◽  
Enantioselective Catalysts

: Many catalysts were tested in asymmetric Michael additions in order to synthesize enantioenriched products. One of the most common reaction types among the Michael reactions is the conjugated addition of malonates to enones making it possible to investigate the structure–activity relationship of the catalysts. The most commonly used Michael acceptors are chalcone, substituted chalcones, chalcone derivatives, cyclic enones, while typical donors may be dimethyl, diethyl, dipropyl, diisopropyl, dibutyl, di-tert-butyl and dibenzyl malonates. This review summarizes the most important enantioselective catalysts applied in these types of reactions.

Synthesis and application of polymer-supported N-sulfonylated aminoalcohols as enantioselective catalysts

Polymer ◽  
2008 ◽  
Vol 49 (6) ◽  
pp. 1512-1519 ◽  
Author(s):  
Chien-An Chen ◽  
Kuo-Hui Wu ◽  
Han-Mou Gau
Keyword(s):  
Polymer Supported ◽  
Enantioselective Catalysts

ChemInform Abstract: Chiral Bisphosphazides as Dual Basic Enantioselective Catalysts.

ChemInform ◽  
2008 ◽  
Vol 39 (42) ◽  
Author(s):  
Hiroshi Naka ◽  
Nobuhiko Kanase ◽  
Masahiro Ueno ◽  
Yoshinori Kondo
Keyword(s):  
Enantioselective Catalysts

High-Throughput Screening of Enantioselective Catalysts by Immunoassay

2002 ◽  
Vol 41 (1) ◽  
pp. 124-127 ◽  
Author(s):  
Frédéric Taran ◽  
Cécile Gauchet ◽  
Barbara Mohar ◽  
Stéphane Meunier ◽  
Alain Valleix ◽  
...  
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Enantioselective Catalysts

A GC-based method for high-throughput screening of enantioselective catalysts

2001 ◽  
Vol 67 (4) ◽  
pp. 389-396 ◽  
Author(s):  
Manfred T. Reetz ◽  
Klaus M. Kühling ◽  
Stephanie Wilensek ◽  
Heribert Husmann ◽  
Ulrich W. Häusig ◽  
...  
Keyword(s):  
High Throughput ◽  
High Throughput Screening ◽  
Enantioselective Catalysts

scholarly journals Histidine-based copper tetrapeptides as enantioselective catalysts for aldol reactions

RSC Advances ◽  
2018 ◽  
Vol 8 (59) ◽  
pp. 34004-34011 ◽  
Author(s):  
Begum Sharifa Zaithun ◽  
AbdulMalek Emilia ◽  
Tahir Mohamed Ibrahim Mohamed ◽  
Crouse Karen Anne ◽  
Abdul Rahman Mohd Basyaruddin
Keyword(s):  
Aldol Reactions ◽  
Enantioselective Catalysts

P5 with the sequence H2N-PGHD-CONH.

Scalable Synthesis of a Chiral Selenium π-Acid Catalyst and Its Use in Enantioselective Iminolactonization of β,γ-Unsaturated Amides

Synlett ◽  
2019 ◽  
Vol 30 (14) ◽  
pp. 1679-1682 ◽  
Author(s):  
Yuta Otsuka ◽  
Yuto Shimazaki ◽  
Hitoshi Nagaoka ◽  
Keiji Maruoka ◽  
Takuya Hashimoto
Keyword(s):  
Carboxylic Acids ◽  
Asymmetric Catalysis ◽  
Acid Catalysis ◽  
Acid Catalyst ◽  
Oxidative Cyclization ◽  
Unsaturated Carboxylic Acids ◽  
Long Time ◽  
Scalable Synthesis ◽  
Enantioselective Catalysts

Chiral selenium π-acid catalysis has for a long time been lagging behind other areas of asymmetric catalysis due to a lack of highly enantioselective catalysts. In this regard, we recently developed the first chiral selenium π-acid catalyst which performs the oxidative cyclization of β,γ-unsaturated carboxylic acids with high enantioselectivities. We report herein our improved synthesis of this chiral selenium catalyst, which allows access to a large quantity of the catalyst as the diselenide. In addition, the catalyst is tested in the oxidative cyclization of N-methoxy β,γ-unsaturated amides to give iminolactones with high enantioselectivities.

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